鉴定产生河豚毒素的深海沉积物细菌。
Identification of deep-sea-sediment bacteria which produce tetrodotoxin.
机构信息
Department of Marine Microbiology, Ocean Research Institute, University of Tokyo, Minamidai, Nakano, Tokyo 164, Japan.
出版信息
Appl Environ Microbiol. 1990 Apr;56(4):1162-3. doi: 10.1128/aem.56.4.1162-1163.1990.
Abstract
Forty-nine bacterial strains were isolated from deep-sea sediments. Among them, 22 strains were shown by the tissue culture assay method to produce sodium channel blockers. For some strains, high-performance liquid chromatography analysis confirmed that the blocker was tetrodotoxin. Tetrodotoxin-producing bacteria seem to be widespread in marine sediment.
摘要
从深海沉积物中分离到 49 株细菌。其中，22 株通过组织培养检测法显示能产生钠离子通道阻断剂。对于某些菌株，高效液相色谱分析证实该阻断剂为河豚毒素。产河豚毒素的细菌似乎广泛存在于海洋沉积物中。
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本文引用的文献
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Occurrence of tetrodotoxin and anhydrotetrodotoxin in Vibrio sp. isolated from the intestines of a xanthid crab, Atergatis floridus.从花纹爱洁蟹（Atergatis floridus）肠道中分离出的弧菌属（Vibrio sp.）中河豚毒素和脱水河豚毒素的存在情况。
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