Ocean Research Institute, University of Tokyo, Minamidai, Nakano, Tokyo 164, Laboratory of Marine Biochemistry, Faculty of Agriculture, University of Tokyo, Bunkyo, Tokyo 113, and Tokyo College of Pharmacy, Hachioji, Tokyo 192-03, Japan.
Appl Environ Microbiol. 1993 Nov;59(11):3934-7. doi: 10.1128/aem.59.11.3934-3937.1993.
The occurrence of tetrodotoxin (TTX) in sediment from Lake Suwa, Japan, was confirmed by a tissue culture assay, high-performance liquid chromatography, and gas chromatography-mass spectrometry. Altogether, 17 TTX-producing bacteria belonging to five genera were isolated from Lake Suwa and Pond Inokasira. Our results indicate that TTX and TTX-producing bacteria occur even in freshwater environments.
日本诹访湖沉积物中存在河豚毒素(TTX),这一发现通过组织培养测定法、高效液相色谱法和气相色谱-质谱法得到了证实。总共从诹访湖和猪谷池分离到了 17 株属于五个属的产 TTX 细菌。研究结果表明,TTX 和产 TTX 细菌甚至存在于淡水环境中。