Badr Hoda, Basen-Engquist Karen, Carmack Taylor Cindy L, de Moor Carl
Department of Behavioral Science, M. D. Anderson Cancer Center, The University of Texas, Houston, TX 77230-1439, USA.
J Behav Med. 2006 Oct;29(5):461-75. doi: 10.1007/s10865-006-9052-9. Epub 2006 May 17.
This study used electronic diaries to examine patterns of mood and physical symptoms within and across days in two independent samples of cancer patients. Twenty-three breast cancer survivors (post-treatment) and 33 ovarian cancer survivors (on chemotherapy) recorded mood and physical symptoms 4 times daily for 7 consecutive days. A series of repeated-measures multilevel models using SAS Proc Mixed were calculated to estimate the degree to which physical symptoms (e.g., pain, fatigue, and nausea) were associated with participants' moods. Across days, mood vectors with a pleasantness component (i.e., happy-sad and calm-anxious) and mood vectors with an arousal component (i.e., active-passive and peppy-tired) were significantly associated with physical symptom severity. Specifically, breast cancer survivors with greater fatigue and pain reported more negative moods (eta2 < or = 0.33). Ovarian cancer survivors with greater fatigue (eta2 < or = 0.35), pain (eta2 < or = 0.04), and nausea (eta2 < or = 0.04) also reported more negative moods. Diurnal analyses showed that happy-sad (eta2 < or = 0.16), active-passive (eta2 < or = 0.27), and peppy-tired moods (eta2 < or = 0.33) were significantly negatively associated with fatigue at each of the four daily assessment times in both samples. Although correlational, our findings are consistent with previous studies suggesting that variations in both pleasant and aroused mood covary with changes in real-time physical symptom reports.
本研究使用电子日记，在两个独立的癌症患者样本中，考察了日内和日间的情绪模式及身体症状。23名乳腺癌幸存者（治疗后）和33名卵巢癌幸存者（化疗中）连续7天每天记录4次情绪和身体症状。使用SAS Proc Mixed计算了一系列重复测量多级模型，以估计身体症状（如疼痛、疲劳和恶心）与参与者情绪相关的程度。在日间，具有愉悦度成分的情绪向量（即快乐-悲伤和平静-焦虑）以及具有唤醒度成分的情绪向量（即活跃-被动和精力充沛-疲惫）与身体症状严重程度显著相关。具体而言，疲劳和疼痛程度较高的乳腺癌幸存者报告了更多负面情绪（eta2≤0.33）。疲劳程度较高（eta2≤0.35）、疼痛程度较高（eta2≤0.04）和恶心程度较高（eta2≤0.04）的卵巢癌幸存者也报告了更多负面情绪。昼夜分析表明，在两个样本中，快乐-悲伤（eta2≤0.16）、活跃-被动（eta2≤0.27）和精力充沛-疲惫情绪（eta2≤0.33）在每日四次评估中的每次都与疲劳显著负相关。尽管是相关性研究，但我们的发现与先前的研究一致，表明愉悦和唤醒情绪的变化与实时身体症状报告的变化共同发生变化。
