Suppr超能文献

通过欧洲癌症研究与治疗组织(EORTC)问卷对晚期结直肠癌患者进行生活质量评估。

Quality of Life assessment through the EORTC questionnaires of colorectal cancer patients in advanced disease stages.

作者信息

Arraras Urdaniz Juan Ignacio, Vera García Ruth, Martínez Aguillo Maite, Manterola Burgaleta Ana, Arias de la Vega Fernando, Salgado Pascual Esteban

机构信息

Servicios de Oncología Médica y Oncología Radioterápica, Hospital de Navarra, Pamplona, Navarra, Spain.

出版信息

Clin Transl Oncol. 2006 Sep;8(9):664-71. doi: 10.1007/s12094-006-0036-6.

Abstract

PURPOSE

The purpose of the present work is to evaluate Quality of Life in a group of colorectal cancer patients in advanced stages of their disease, along a standard chemotherapy treatment protocol, through the EORTC core questionnaire QLQ-C30 and the colorectal cancer module QLQ-CR38. These two questionnaires had previously been validated in our country. The present study has the novelty of its use during the chemotherapy treatment.

MATERIALS AND METHODS

A consecutive sample of 44 colon o rectal cancer patients in stage IV, from an initial group of 46 patients who were addressed, have filled in the questionnaires, in three moments during their treatment process. Clinical and demographic data have also been recorded. Quality of Life scores and changes in them among the three assessments have been calculated.

RESULTS

The quality of life scores of patients who have followed the treatment have been >70 points (100) in most dimensions, and has shown similar to the clinical data. Changes of >20 points in the quality of life scores during the treatment process appear in areas related to toxicity, fatigue and insomnia. Quality of life has been stable or has had small changes (between 10 and 20 points) in most dimensions.

CONCLUSIONS

Quality of Life in the present sample has been good in general. The treatment has been administered to patients who could tolerate it adequately.

摘要

目的

本研究旨在通过欧洲癌症研究与治疗组织(EORTC)核心问卷QLQ-C30和结直肠癌模块QLQ-CR38,对一组处于疾病晚期的结直肠癌患者在标准化疗治疗方案期间的生活质量进行评估。这两份问卷此前已在我国得到验证。本研究的新颖之处在于其在化疗治疗期间的使用。

材料与方法

从最初收治的46例患者中选取44例IV期结肠直肠癌患者的连续样本,在治疗过程中的三个时间点填写问卷。还记录了临床和人口统计学数据。计算了生活质量得分以及三次评估之间的得分变化。

结果

接受治疗的患者在大多数维度上的生活质量得分均>70分(满分100分),且与临床数据相似。治疗过程中生活质量得分变化>20分的情况出现在与毒性、疲劳和失眠相关的领域。生活质量在大多数维度上保持稳定或有小的变化(10至20分之间)。

结论

本样本中的生活质量总体良好。该治疗方案应用于能够充分耐受的患者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验