Johnson N, Fooks A R, Valtchovski R, Müller T
Rabies and Wildlife Zoonoses Group, Veterinary Laboratories Agency-Weybridge, Woodham Lane, Addlestone, Surrey KT15 3NB, UK.
Vet Microbiol. 2007 Feb 25;120(1-2):71-6. doi: 10.1016/j.vetmic.2006.10.012. Epub 2006 Oct 20.
Rabies remains endemic in a number of reservoir species throughout southeast Europe. To investigate the relationship between rabies viruses within this region we have compared rabies virus nucleoprotein sequence data from a diverse panel of rabies samples from Bulgaria with available data from countries in the Balkan Peninsula. This analysis provides a first description of rabies isolates in Bulgaria and suggests that there is evidence for wildlife-mediated movement of rabies with countries to the west of Bulgaria including Serbia and Bosnia-Herzegovina but no evidence for a link with rabies foci in Turkey. We speculate that natural barriers such as the Balkan mountains may play a significant role in constraining the southerly spread of rabies in southeast Europe.
狂犬病在东南欧的许多储存宿主物种中仍然流行。为了研究该地区狂犬病病毒之间的关系，我们将来自保加利亚的各种狂犬病样本的狂犬病病毒核蛋白序列数据与巴尔干半岛各国的现有数据进行了比较。该分析首次描述了保加利亚的狂犬病病毒分离株，并表明有证据显示狂犬病通过野生动物在保加利亚以西的国家（包括塞尔维亚和波斯尼亚和黑塞哥维那）之间传播，但没有证据表明与土耳其的狂犬病疫源地存在联系。我们推测，诸如巴尔干山脉等天然屏障可能在限制狂犬病在东南欧向南传播方面发挥了重要作用。
