修饰对某些嗜B性鼠白血病病毒易感性的新基因座。
New gene locus modifying susceptibility to certain B-tropic murine leukemia viruses.
作者信息
Declève A, Niwa O, Kojola J, Kaplan H S
出版信息
Proc Natl Acad Sci U S A. 1976 Feb;73(2):585-90. doi: 10.1073/pnas.73.2.585.
Abstract
A new gene, SRV, the dominant allele of which occurs in mice of strain C57BL, independently modifies the slope ("hitness") and level of sensitivity of the titration curves obtained when one subclass of B-tropic murine leukemia viruses is propagated on mouse embryo cells of nonpermissive Fv-1 genotypes. Replication of another subclass of B-tropic viruses is not modified with respect to hitness, and that of N-tropic viruses is not affected.
摘要
一个新基因SRV，其显性等位基因出现在C57BL品系小鼠中，当一类嗜B性鼠白血病病毒在非允许性Fv-1基因型的小鼠胚胎细胞上增殖时，该基因独立地改变所获得的滴定曲线的斜率（“适应性”）和敏感性水平。另一类嗜B性病毒的复制在适应性方面未被改变，而嗜N性病毒的复制则不受影响。
相似文献
1
New gene locus modifying susceptibility to certain B-tropic murine leukemia viruses.修饰对某些嗜B性鼠白血病病毒易感性的新基因座。
Proc Natl Acad Sci U S A. 1976 Feb;73(2):585-90. doi: 10.1073/pnas.73.2.585.
2
Genetic transmission of endogenous N- and B-tropic murine leukemia viruses in low-leukemic strain C57BL/6.内源性N型和B型嗜性小鼠白血病病毒在低白血病C57BL/6品系中的遗传传递
J Virol. 1975 Feb;15(2):332-7. doi: 10.1128/JVI.15.2.332-337.1975.
3
Replication of mouse-tropic and xenotropic strains of murine leukemia virus in human x mouse hybrid cells.鼠白血病病毒的嗜小鼠株和异嗜性株在人 - 小鼠杂交细胞中的复制。
Proc Natl Acad Sci U S A. 1974 Jul;71(7):2642-5. doi: 10.1073/pnas.71.7.2642.
4
Inherited resistance to N- and B-tropic murine leukemia viruses in vitro: titration patterns in strains SIM and SIM.R congenic at the Fv-1 locus.体外对N-和B-嗜性鼠白血病病毒的遗传抗性：Fv-1基因座同基因的SIM和SIM.R品系中的滴定模式
J Virol. 1976 May;18(2):473-80. doi: 10.1128/JVI.18.2.473-480.1976.
5
Effect of the Fv-1 locus on the titration of murine leukemia viruses.Fv-1基因座对小鼠白血病病毒滴定的影响。
J Virol. 1975 Dec;16(6):1593-8. doi: 10.1128/JVI.16.6.1593-1598.1975.
6
Genetic evidence for a product of the Fv-1 locus that transfers resistance to mouse leukemia viruses.Fv-1基因座产物传递对小鼠白血病病毒抗性的遗传证据。
J Virol. 1976 Dec;20(3):589-96. doi: 10.1128/JVI.20.3.589-596.1976.
7
Mouse strain resistant to N-, B-, and NB-tropic murine leukemia viruses.对N-、B-和NB嗜性鼠白血病病毒具有抗性的小鼠品系。
J Virol. 1976 Nov;20(2):436-40. doi: 10.1128/JVI.20.2.436-440.1976.
8
Reciprocal inhibition of mouse leukemia virus infection by Fv-1 allele cell extracts.Fv-1等位基因细胞提取物对小鼠白血病病毒感染的相互抑制作用。
Proc Natl Acad Sci U S A. 1974 Oct;71(10):4241-5. doi: 10.1073/pnas.71.10.4241.
9
Inherited resistance to N- and B-tropic murine leukemia viruses in vitro: evidence that congenic mouse strains SIM and SIM.R differ at the Fv-1 locus.体外对N-和B-嗜性鼠白血病病毒的遗传抗性：同基因小鼠品系SIM和SIM.R在Fv-1基因座存在差异的证据。
Virology. 1972 Nov;50(2):339-48. doi: 10.1016/0042-6822(72)90385-6.
10
Bvr-1, a restriction locus of a type C RNA virus in the feline cellular genome: pleiotropic restriction of endogenous BALB virus in cat X mouse somatic cell hybrids.Bvr-1，猫细胞基因组中一种C型RNA病毒的限制位点：猫X小鼠体细胞杂种中内源性BALB病毒的多效性限制
J Exp Med. 1978 Jan 1;147(1):219-32. doi: 10.1084/jem.147.1.219.
引用本文的文献
1
Characterization of an infective molecular clone of the B-tropic, ecotropic BL/Ka(B) murine retrovirus genome.嗜B性、亲嗜性BL/Ka(B)小鼠逆转录病毒基因组感染性分子克隆的特性分析
J Virol. 1982 Oct;44(1):217-25. doi: 10.1128/JVI.44.1.217-225.1982.
2
Characterization of N-type and dually permissive cells segregated from mouse fibroblasts whose Fv-1 phenotype could be modified by another independently segregating gene(s).从Fv-1表型可被另一个独立分离的基因修饰的小鼠成纤维细胞中分离出的N型和双重允许细胞的特征。
J Virol. 1982 Jan;41(1):145-52. doi: 10.1128/JVI.41.1.145-152.1982.
3
Cytotypically specific transfecting activity of DNA from C57BL/Ka mouse cells producing thymotropic in contrast to nonthymotropic retroviruses.与非嗜胸腺性逆转录病毒相反，来自产生嗜胸腺性的C57BL/Ka小鼠细胞的DNA的细胞类型特异性转染活性。
Proc Natl Acad Sci U S A. 1980 Oct;77(10):6189-93. doi: 10.1073/pnas.77.10.6189.
4
Effect of Fv-1 gene product on synthesis of linear and supercoiled viral DNA in cells infected with murine leukemia virus.Fv-1基因产物对感染小鼠白血病病毒的细胞中线性和超螺旋病毒DNA合成的影响。
J Virol. 1980 Jan;33(1):183-95. doi: 10.1128/JVI.33.1.183-195.1980.
5
Development and characterization of an Fv-1-sensitive retrovirus-packaging system: single-hit titration kinetics observed in restrictive cells.Fv-1敏感逆转录病毒包装系统的开发与特性分析：在限制细胞中观察到的单打击滴定动力学
J Virol. 1989 Jun;63(6):2592-7. doi: 10.1128/JVI.63.6.2592-2597.1989.
6
Genetics of resistance of animals to viruses: I. Introduction and studies in mice.动物对病毒的抗性遗传学：I. 引言及小鼠研究
Adv Virus Res. 1978;23:269-348. doi: 10.1016/s0065-3527(08)60102-5.
7
Biological and serological characterization of radiation leukemia virus.辐射白血病病毒的生物学和血清学特性
Proc Natl Acad Sci U S A. 1976 Dec;73(12):4675-9. doi: 10.1073/pnas.73.12.4675.
本文引用的文献
1
Derivation of a murine lymphoid leukemia virus.一种鼠类淋巴白血病病毒的衍生
J Natl Cancer Inst. 1962 Jun;28:1291-303.
2
Leukemogenic activity of filtrates from radiation-induced lymphoid tumors of mice.小鼠辐射诱导淋巴肿瘤滤液的致白血病活性。
Science. 1959 Aug 14;130(3372):387-8. doi: 10.1126/science.130.3372.387.
3
Inheritance of susceptibility to Friend mouse leukemia virus. V. Introduction of a gene responsible for susceptibility in the genetic complement of resistant mice.对弗瑞德小鼠白血病病毒易感性的遗传。V. 将负责易感性的基因引入抗性小鼠的遗传互补中。
J Virol. 1969 Jun;3(6):543-8. doi: 10.1128/JVI.3.6.543-548.1969.
4
Fv-2: identification and location of a second gene governing the spleen focus response to Friend leukemia virus in mice.Fv-2：小鼠中控制对Friend白血病病毒的脾集落反应的第二个基因的鉴定与定位
J Natl Cancer Inst. 1970 Jul;45(1):163-9.
5
On the natural history of the murine leukemias: presidential address.论鼠白血病的自然史：主席致辞
Cancer Res. 1967 Aug;27(8):1325-40.
6
Host restriction of friend leukemia virus; fate of input virion RNA.宿主对Friend白血病病毒的限制；输入病毒粒子RNA的命运
Cell. 1974 Aug;2(4):271-7. doi: 10.1016/0092-8674(74)90021-x.
7
Rapid in vivo assay for murine lymphatic leukaemia viruses.小鼠淋巴白血病病毒的快速体内检测法
Nature. 1974 Nov 1;252(5478):79-81. doi: 10.1038/252079a0.
8
An improved murine leukemia virus immunofluorescence assay.一种改进的鼠白血病病毒免疫荧光测定法。
Virology. 1974 Feb;57(2):491-502. doi: 10.1016/0042-6822(74)90188-3.
9
Growth of pseudotypes of vesicular stomatitis virus with N-tropic murine leukemia virus coats in cells resistant to N-tropic viruses.水泡性口炎病毒假型在对N-嗜性病毒具有抗性的细胞中与N-嗜性鼠白血病病毒包膜的生长情况。
J Virol. 1973 Sep;12(3):659-62. doi: 10.1128/JVI.12.3.659-662.1973.
10
Host restriction of Friend leukemia virus. Role of the viral outer coat.弗瑞德白血病病毒的宿主限制。病毒外膜的作用。
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2549-53. doi: 10.1073/pnas.70.9.2549.
Zotero 插件