Dobrev Hristo
Department of Dermatology, Medical University, Plovdiv, Bulgaria.
J Cosmet Dermatol. 2007 Jun;6(2):113-8. doi: 10.1111/j.1473-2165.2007.00306.x.
Some botanical compounds are considered useful to reduce sebum production. Aim To evaluate the efficacy of a sebum control cream containing polyphenol-rich extract from saw palmetto, sesame seeds, and argan oil in subjects with oily facial skin.
The study was carried out during the winter months (January and February). A total of 20 healthy volunteers (9 male and 11 female, aged 17-50 years, 16 with oily skin and 4 with combined skin) were studied. The test product was applied twice daily to the face for a period of 4 weeks. A clinical assessment and instrumental measurements were done before and after the treatment period. Casual sebum level on the forehead and both cheeks was determined with a photometric device (Sebumeter). The quantity of sebum on the midforehead was determined using sebum collector foils (Sebufix), which were then evaluated with skin camera Visioscope and software SELS (Surface Evaluation of the Living Skin). A subjective evaluation questionnaire regarding the cosmetic characteristics, tolerance, and efficacy of the product was filled out by the volunteers at the end of study.
The product was very well accepted by all the volunteers. A visible sebum-regulating efficacy was reported in 95% of them. After 4 weeks of treatment, the clinical assessment scores decreased by 33%. There was a significant reduction in the casual sebum level by 20% and area covered with oily spots by 42%. The number of active sebaceous glands remained unaltered.
These results objectively and quantitatively show the efficacy of the sebum control cream tested to reduce the greasiness and improve the appearance of oily facial skin.
一些植物化合物被认为有助于减少皮脂分泌。目的：评估一种含有锯棕榈、芝麻籽富含多酚提取物和摩洛哥坚果油的控油面霜对油性面部皮肤受试者的疗效。
研究在冬季（1月和2月）进行。共研究了20名健康志愿者（9名男性和11名女性，年龄17 - 50岁，16名油性皮肤和4名混合性皮肤）。测试产品每天两次涂抹于面部，持续4周。在治疗期前后进行临床评估和仪器测量。使用光度测量仪（皮脂测定仪）测定前额和双颊的皮脂水平。使用皮脂收集箔（皮脂固定器）测定前额中部的皮脂量，然后用皮肤相机Visioscope和软件SELS（活体皮肤表面评估）进行评估。志愿者在研究结束时填写了一份关于产品的美容特性、耐受性和疗效的主观评估问卷。
该产品被所有志愿者很好地接受。95%的志愿者报告有明显的皮脂调节功效。治疗4周后，临床评估得分下降了33%。随意皮脂水平显著降低20%，油性斑点覆盖面积减少42%。活跃皮脂腺的数量保持不变。
这些结果客观且定量地显示了所测试的控油面霜在减少油腻感和改善油性面部皮肤外观方面的功效。
