Ehrich Kathryn, Williams Clare, Farsides Bobbie, Sandall Jane, Scott Rosamund
School of Social Science and Public Policy, King's College London, London, UK.
Sociol Health Illn. 2007 Nov;29(7):1091-106. doi: 10.1111/j.1467-9566.2007.01021.x.
The technique of preimplantation genetic diagnosis (PGD) is commonly explained as a way of checking the genes of embryos produced by IVF for serious genetic diseases. However, complex accounts of this technique emerged during ethics discussion groups held for PGD staff. These form part of a study exploring the social processes, meanings and institutions that frame and produce 'ethical problems' for practitioners, scientists and others working in the specialty of PGD in the UK. Two 'grey areas' raised by staff are discussed in terms of how far staff are, or in the future may be, able to support autonomous choices of women/couples: accepting 'carrier' embryos within the goal of creating a 'healthy' child; and sex selection of embryos for social reasons. These grey areas challenged the staff's resolve to offer individual informed choice, in the face of their awareness of possible collective social effects that might ensue from individual choices. We therefore argue that these new forms of choice pose a challenge to conventional models of individual autonomy used in UK genetic and reproductive counselling, and that 'relational autonomy' may be a more suitable ethical model to describe the ethical principles being drawn on by staff working in this area.
植入前基因诊断(PGD)技术通常被解释为一种检查体外受精产生的胚胎基因是否患有严重遗传疾病的方法。然而,在为PGD工作人员举办的伦理讨论小组中出现了对该技术的复杂描述。这些是一项研究的一部分,该研究探讨了为英国PGD专业的从业者、科学家和其他人员构建并产生“伦理问题”的社会过程、意义和制度。工作人员提出的两个“灰色地带”,将根据工作人员在多大程度上能够或在未来可能能够支持女性/夫妇的自主选择来进行讨论:在创造“健康”孩子的目标范围内接受“携带”胚胎;以及出于社会原因对胚胎进行性别选择。面对他们意识到个人选择可能产生的集体社会影响,这些灰色地带挑战了工作人员提供个人知情选择的决心。因此,我们认为这些新的选择形式对英国基因和生殖咨询中使用的传统个人自主模式构成了挑战,并且“关系自主性”可能是一种更合适的伦理模式,用以描述该领域工作人员所借鉴的伦理原则。