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使用鼠诺如病毒作为替代物来评估人类诺如病毒对消毒剂的抗性。

Use of murine norovirus as a surrogate to evaluate resistance of human norovirus to disinfectants.

作者信息

Belliot Gaël, Lavaux Amandine, Souihel Donya, Agnello Davide, Pothier Pierre

机构信息

Laboratoire de Virologie, Centre National de Référence des Virus Entériques, Centre Hospitalier Universitaire de Dijon, 7 boulevard Jeanne d'Arc, 21079 Dijon Cedex, France.

出版信息

Appl Environ Microbiol. 2008 May;74(10):3315-8. doi: 10.1128/AEM.02148-07. Epub 2008 Mar 31.

Abstract

Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.

摘要

鼠诺如病毒(MNV)被用作替代品,以研究人类诺如病毒对医院使用的消毒剂的抗性。MNV对酒精、酒精擦手液、漂白剂和聚维酮碘基消毒剂敏感。实时逆转录聚合酶链反应结果表明,病毒RNA的存在与传染性病毒的存在不相关。

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