Liu Wen-Bo, He Hu, Dai Li-Xin, You Shu-Li
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
Org Lett. 2008 May 1;10(9):1815-8. doi: 10.1021/ol800409d. Epub 2008 Apr 3.
Highly regio- and enantioselective Ir-catalyzed Friedel-Crafts type allylic alkylation of indoles have been realized using [Ir(COD)Cl]2/phosphoramidite ligand 1a, affording the branched products with up to >97/3 branched-linear ratio and 92% ee.
使用[Ir(COD)Cl]2/亚磷酰胺配体1a实现了铱催化的吲哚的高度区域和对映选择性傅克型烯丙基烷基化反应，得到支链产物，支链与直链比例高达>97/3，对映体过量值为92%。
