Patrick Charles W, Uthamanthil Rajesh, Beahm Elisabeth, Frye Cindy
Department of Biomedical Engineering, The University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.
Tissue Eng Part B Rev. 2008 Jun;14(2):167-78. doi: 10.1089/ten.teb.2007.0402.
There is a critical need for adequate reconstruction of soft tissue defects resulting from tumor resection, trauma, and congenital abnormalities. To be sure, adipose tissue engineering strategies offer promising solutions. However, before clinical translation can occur, efficacy must be proven in animal studies. The aim of this review is to provide an overview of animal models currently employed for adipose tissue engineering.
对于因肿瘤切除、创伤和先天性异常导致的软组织缺损进行充分重建有着迫切需求。诚然,脂肪组织工程策略提供了有前景的解决方案。然而,在进行临床转化之前,必须在动物研究中证明其有效性。本综述的目的是概述目前用于脂肪组织工程的动物模型。