Freedman R R
Lafayette Clinic, Detroit, Michigian 48207.
Biofeedback Self Regul. 1991 Jun;16(2):95-115. doi: 10.1007/BF01000184.
Research on the physiological mechanisms of finger temperature biofeedback with normal subjects and Raynaud's disease patients is reviewed. Studies conducted in the author's laboratory have shown that feedback-induced vasodilation is mediated through a non-neural, beta-adrenergic mechanism rather than through reductions in sympathetic nervous system activation. In contrast, feedback-induced vasoconstriction is mediated through the traditional, sympathetic nervous pathway. When used with primary Raynaud's disease patients, feedback-induced vasodilation has achieved reductions in reported symptom frequency ranging from 66% to 92% in controlled investigations. Future research directions are discussed.
综述了关于正常受试者和雷诺病患者手指温度生物反馈生理机制的研究。作者实验室进行的研究表明，反馈诱导的血管舒张是通过非神经的β-肾上腺素能机制介导的，而不是通过交感神经系统激活的降低。相比之下，反馈诱导的血管收缩是通过传统的交感神经通路介导的。当用于原发性雷诺病患者时，在对照研究中，反馈诱导的血管舒张已使报告的症状频率降低了66%至92%。讨论了未来的研究方向。
