Christie D, Robinson K, Gordon I, Bisby J
Discipline of Environment and Occupational Health, University of Newcastle, Australia.
Br J Ind Med. 1991 Aug;48(8):511-4. doi: 10.1136/oem.48.8.511.
This paper reports incidence of cancer in employees of the Australian petroleum industry from 1981 to 1989. Two surveys by personal interview incorporated more than 15,000 employees, representing 92% of the eligible population. Subjects were included in the analysis after completing five years of service in the industry. At the time of this report the cohort did not include sufficiently large numbers of women for useful analysis; results presented are restricted to the men. On 31 December 1989, 50,254 person-years of observation had accumulated in the men with 152 incident cancers reported. The standardised incidence ratio (SIR) analysis showed overall cancer rates close to those of the national population. Whereas deficits were seen in some cancer sites, notably lung cancer (SIR 0.5, 95% confidence internal (95% CI) 0.3-0.9), incidence rates for some other cancer sites suggested increased risk. An excess of observed over expected cases was present in all subcategories of lymphohaematopoietic cancer except Hodgkin's disease (no cases), and was most apparent in myeloid leukaemia (SIR 4.0, 95% CI 1.6-8.2). The other major site with a raised number of cases observed over expected was melanoma (SIR 1.4, 95% CI 0.8-2.1).
本文报告了1981年至1989年澳大利亚石油行业员工的癌症发病率。通过个人访谈进行的两项调查涵盖了超过15000名员工，占符合条件人口的92%。在该行业服务满五年的受试者被纳入分析。在撰写本报告时，该队列中的女性数量不足，无法进行有效的分析；所呈现的结果仅限于男性。截至1989年12月31日，男性累积观察人年数为50254人年，报告了152例新发癌症病例。标准化发病率（SIR）分析显示，总体癌症发病率接近全国人口水平。虽然在某些癌症部位发现发病率较低，尤其是肺癌（SIR 0.5，95%置信区间（95%CI）0.3 - 0.9），但其他一些癌症部位的发病率显示风险增加。除霍奇金病（无病例）外，淋巴造血系统癌症的所有亚类中观察到的病例数均超过预期，在髓细胞白血病中最为明显（SIR 4.0，95%CI 1.6 - 8.2）。另一个观察到的病例数超过预期的主要部位是黑色素瘤（SIR 1.4，95%CI 0.8 - 2.1）。
