Vesović-Potić Vladislava, Mustur Dusan, Stanisavljević Dejana, Ille Tatjana, Ille Mihailo
Clinical Center of Serbia, Center of Physical Medicine and Rehabilitation, School of Medicine, University of Belgrade, Belgrade, Serbia.
Rheumatol Int. 2009 Jun;29(8):879-84. doi: 10.1007/s00296-008-0759-5. Epub 2009 Jan 27.
The aim of this study was to assess spinal mobility status and Quality of life (QoL) of patients with ankylosing spondylitis (AS) and determine the relationship between spinal mobility and measures of clinical condition including QoL. A total of 74 patients with AS were included in this study. Disease specific instruments Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) were applied, and mobility testing: occiput-wall distance and chest expansion. QoL was assessed by the Short Form-36 (SF-36). The mean age was 48.5 years; there were significant correlations between BASMI score and age (P < 0.001), disease duration (P < 0.001), symptoms duration (P < 0.001) and BASFI (P < 0.001). BASMI was negatively correlated with SF-36 physical function subscale (P < 0.001) and general health subscale (P = 0.029). In multivariate regression analysis, BASFI score (P < 0.001) was independently associated factor with physical function domain of SF-36. This study showed that in AS spinal mobility measures are associated with physical function, general health, emotional role and mental health domains of QoL.
本研究旨在评估强直性脊柱炎（AS）患者的脊柱活动度状况和生活质量（QoL），并确定脊柱活动度与包括QoL在内的临床状况指标之间的关系。本研究共纳入74例AS患者。应用了疾病特异性工具，如巴斯强直性脊柱炎测量指数（BASMI）、巴斯强直性脊柱炎疾病活动指数（BASDAI）和巴斯强直性脊柱炎功能指数（BASFI），并进行了活动度测试：枕墙距和胸廓活动度。通过简短健康调查问卷（SF-36）评估生活质量。平均年龄为48.5岁；BASMI评分与年龄（P<0.001）、病程（P<0.001）、症状持续时间（P<0.001）和BASFI（P<0.001）之间存在显著相关性。BASMI与SF-36身体功能分量表（P<0.001）和总体健康分量表（P=0.029）呈负相关。在多变量回归分析中，BASFI评分（P<0.001）是SF-36身体功能领域的独立相关因素。本研究表明，在AS中，脊柱活动度测量与QoL的身体功能、总体健康、情感角色和心理健康领域相关。
