Ghil Heh-Myung, Yoo Jong-Hyeon, Jung Woo-Sung, Chung Tae-Ho, Youn Hwa-Young, Hwang Cheol-Yong
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea.
J Vet Sci. 2009 Mar;10(1):67-72. doi: 10.4142/jvs.2009.10.1.67.
Discovery of Helicobacter (H.) pylori has led to a fundamental change in our understanding of gastric diseases in humans. Previous studies have found various Helicobacter spp. in dogs and cats, and pets have been questioned as a zoonotic carrier. The present study surveyed the Helicobacter infections and investigated the presence of H. felis and H. pylori infections in domestic and feral cats in Korea. Sixty-four domestic cats and 101 feral cats were selected from an animal shelter. Saliva and feces were evaluated by Helicobacter genus-specific polymerase chain reaction (PCR). Genus-specific PCR positive samples were further evaluated for H. felis and H. pylori using specific primer pairs. Thirty-six of 64 (56.3%) samples from domestic cats and 92 of 101 (91.1%) samples from feral cats were PCR positive; the positive rate of feces samples was higher than that of saliva samples in both groups. H. felis and H. pylori species-specific PCR was uniformly negative. The prevalence of Helicobacter spp. in feral cats was approximately two-fold higher than that of domestic cats. The fecal-oral route may be more a common transmission route not only between cats but also in humans.
幽门螺杆菌的发现使我们对人类胃部疾病的认识发生了根本性变化。此前的研究在狗和猫身上发现了各种幽门螺杆菌属细菌，宠物也被质疑是一种人畜共患病原体携带者。本研究调查了韩国家猫和野猫的幽门螺杆菌感染情况，并研究了猫胃螺杆菌和幽门螺杆菌感染的存在情况。从一个动物收容所挑选了64只家猫和101只野猫。通过幽门螺杆菌属特异性聚合酶链反应（PCR）对唾液和粪便进行评估。对属特异性PCR阳性样本使用特异性引物对进一步评估猫胃螺杆菌和幽门螺杆菌。64份家猫样本中有36份（56.3%）、101份野猫样本中有92份（91.1%）PCR呈阳性；两组粪便样本的阳性率均高于唾液样本。猫胃螺杆菌和幽门螺杆菌种特异性PCR均为阴性。野猫中幽门螺杆菌属的患病率比家猫高约两倍。粪-口途径可能不仅是猫之间，也是人类之间更常见的传播途径。
