Constantine N T, Fathi Sheba M, Corwin A L, Danahy R S, Callahan J D, Watts D M
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt.
Epidemiol Infect. 1991 Oct;107(2):429-33. doi: 10.1017/s0950268800049074.
The prevalence of antibodies to human T-cell lymphotropic virus type I (HTLV-I) was determined in high-risk groups and normal adults in Egypt. Among 647 individuals tested, 6 (0.9%) were confirmed positive by western blot analysis. These included 2 (0.7%) of 279 drug addicts, 1 (3.3%) of 30 patients with sexually transmitted diseases, and 3 (2.2%) of 133 healthy individuals. Antibody was not detected in 47 blood recipients or 158 prostitutes. There was no correlation between sex or geographical location and HTLV-I infection. Fifty-three of the 647 sera (8%) were initially reactive by ELISA, but only 12 sera were repeatedly reactive. Since only 4 of these repeatedly reactive sera were confirmed by the western blot, the frequency of false positives using the DuPont screening ELISA was 1.2% (8/643). Two additional sera, confirmed positive by western blot, had been reactive, but not repeatedly, by ELISA. In comparison to the prevalence of HTLV-I antibody among risk groups in many parts of the world, the prevalence in Egypt was low.
在埃及的高危人群和正常成年人中测定了抗I型人类嗜T细胞病毒（HTLV-I）抗体的流行情况。在接受检测的647人中，6人（0.9%）经免疫印迹分析确认为阳性。其中包括279名吸毒者中的2人（0.7%）、30名性传播疾病患者中的1人（3.3%）以及133名健康个体中的3人（2.2%）。47名输血者和158名妓女中未检测到抗体。性别或地理位置与HTLV-I感染之间无相关性。647份血清中有53份（8%）最初通过酶联免疫吸附测定（ELISA）呈反应性，但只有12份血清反复呈反应性。由于这些反复呈反应性的血清中只有4份经免疫印迹确认为阳性，因此使用杜邦筛查ELISA的假阳性率为1.2%（8/643）。另外两份经免疫印迹确认为阳性的血清，ELISA检测时呈反应性，但未反复呈反应性。与世界许多地区高危人群中HTLV-I抗体的流行率相比，埃及的流行率较低。
