Okochi K, Sato H, Hinuma Y
Vox Sang. 1984;46(5):245-53. doi: 10.1111/j.1423-0410.1984.tb00083.x.
Possible transmission of adult T cell leukemia virus (ATLV) by blood transfusion was studied retrospectively. Of 41 recipients of whole blood or blood components containing cells from donors having antibodies to antigen that is associated with ATLV (anti-ATLA), 26 (63.4%) produced anti-ATLA. However, no anti-ATLA was detected in all 14 recipients of fresh-frozen plasma prepared from anti-ATLA-positive donors. None of 252 recipients of blood with cell components from anti-ATLA-negative donors produced anti-ATLA. The development of anti-ATLA in the recipients may correspond to antibody production after establishment of primary infection with ATLV that is associated with cells in blood from anti-ATLA-positive donors who are ATLV carriers.
对成人T细胞白血病病毒（ATLV）通过输血传播的可能性进行了回顾性研究。在41名接受含有来自对与ATLV相关抗原具有抗体（抗ATLA）的献血者细胞的全血或血液成分的受血者中，26名（63.4%）产生了抗ATLA。然而，在所有14名接受由抗ATLA阳性献血者制备的新鲜冰冻血浆的受血者中均未检测到抗ATLA。252名接受来自抗ATLA阴性献血者的含细胞成分血液的受血者中，无一产生抗ATLA。受血者中抗ATLA的产生可能与原发性感染ATLV后产生抗体相对应，该感染与来自作为ATLV携带者的抗ATLA阳性献血者血液中的细胞有关。
