Tagliapietra Valentina, Rosà Roberto, Hauffe Heidi C, Laakkonen Juha, Voutilainen Liina, Vapalahti Olli, Vaheri Antti, Henttonen Heikki, Rizzoli Annapaola
Edmund Mach Foundation-Istituto Agrario di San Michele all'Adige, San Michele all'Adige, Italy.
Emerg Infect Dis. 2009 Jul;15(7):1019-25. doi: 10.3201/eid1507.081524.
We determined the prevalence of infection with lymphocytic choriomeningitis virus (LCMV) among small mammals in northern Italy and analyzed long-term dynamics of LCMV in a rodent population in the province of Trento. LCMV is circulating among the most widespread and common wild rodent species in this area (Apodemus flavicollis, Myodes glareolus, and Microtus arvalis); overall prevalence is 6.8%. During 2000-2006, intensive monitoring of LCMV in a population of yellow-necked mice (A. flavicollis) showed a positive correlation between prevalence of infection and rodent density. At the individual level, weight and sex appeared to correlate with antibody prevalence, which suggests that horizontal transmission of LCMV occurs principally among heavier, older males and occurs during fighting. Isolation and genetic characterization of this virus will be the crucial next steps for a better understanding of its ecology.
我们测定了意大利北部小型哺乳动物中淋巴细胞性脉络丛脑膜炎病毒（LCMV）的感染率，并分析了特伦托省啮齿动物种群中LCMV的长期动态。LCMV在该地区分布最广且常见的野生啮齿动物物种（黄颈姬鼠、林姬鼠和草原田鼠）中传播；总体感染率为6.8%。在2000年至2006年期间，对黄颈姬鼠种群进行的LCMV密集监测显示，感染率与啮齿动物密度之间呈正相关。在个体层面，体重和性别似乎与抗体阳性率相关，这表明LCMV的水平传播主要发生在较重、年龄较大的雄性之间，且发生在打斗过程中。对该病毒进行分离和基因特征分析将是进一步了解其生态学的关键后续步骤。
