Ohta Kouichi, Sato Atsuko, Fukui Emi
Department of Ophthalmology, Matsumoto Dental University, shiojiri, Nagano, Japan.
Clin Ophthalmol. 2009;3:423-8. doi: 10.2147/opth.s6108. Epub 2009 Aug 3.
To describe the morphology of the retina at the convalescent stage of acute zonal occult outer retinopathy (AZOOR) from images obtained by spectral domain optical coherence tomography (SD-OCT).
The visual fields, electroretinograms (ERGs), and OCT images were reviewed in two women aged 24 and 33 years. The patients were followed for one and four years, respectively.
In both cases, the anterior and posterior segments were almost normal, although both patients had a sudden unilateral vision decrease and photopsia. Goldmann perimetry revealed enlarged blind spots and scotomas. The ERGs were reduced in both cases. SD-OCT showed that the junction of the inner and outer segment, the IS/OS line, of the photoreceptors was irregular or lost in the affected retinas. The retina in these areas was thinner due to a decrease in the thickness of both the outer nuclear layer (ONL) and inner nuclear layer (INL) in Case 2.
The decrease in retinal thickness at the convalescent stage of AZOOR is most likely due to a shortening of not only the photoreceptors and ONL but also to a thinning of the INL in a severe case.
通过光谱域光学相干断层扫描（SD-OCT）获得的图像描述急性区域性隐匿性外层视网膜病变（AZOOR）恢复期视网膜的形态。
对两名年龄分别为24岁和33岁的女性患者的视野、视网膜电图（ERG）和OCT图像进行了回顾。两名患者分别随访了1年和4年。
在这两个病例中，尽管两名患者均突然出现单侧视力下降和闪光感，但眼前节和后节几乎正常。Goldmann视野检查显示盲点扩大和暗点。两个病例的ERG均降低。SD-OCT显示，在受影响的视网膜中，光感受器的内节和外节交界处（IS/OS线）不规则或消失。在病例2中，由于外层核层（ONL）和内层核层（INL）厚度均减少，这些区域的视网膜变薄。
AZOOR恢复期视网膜厚度的降低很可能不仅是由于光感受器和ONL缩短，在严重病例中还由于INL变薄。
