纳米技术在癌症治疗方面的进展。
Advances of cancer therapy by nanotechnology.
机构信息
Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
出版信息
Cancer Res Treat. 2009 Mar;41(1):1-11. doi: 10.4143/crt.2009.41.1.1. Epub 2009 Mar 31.
Abstract
Recent developments in nanotechnology offer researchers opportunities to significantly transform cancer therapeutics. This technology has enabled the manipulation of the biological and physicochemical properties of nanomaterials to facilitate more efficient drug targeting and delivery. Clinical investigations suggest that therapeutic nanoparticles can enhance efficacy and reduced side effects compared with conventional cancer therapeutic drugs. Encouraged by rapid and promising progress in cancer nanotechnology, researchers continue to develop novel and efficacious nanoparticles for drug delivery. The use of therapeutic nanoparticles as unique drug delivery systems will be a significant addition to current cancer therapeutics.
摘要
纳米技术的最新发展为研究人员提供了重大改变癌症治疗方法的机会。这项技术使人们能够操纵纳米材料的生物和物理化学特性，以促进更有效的药物靶向和传递。临床研究表明，与传统的癌症治疗药物相比，治疗纳米粒子可以提高疗效并降低副作用。由于癌症纳米技术的快速和有希望的进展，研究人员继续开发用于药物输送的新型有效纳米粒子。治疗纳米粒子作为独特的药物输送系统的使用将是当前癌症治疗方法的重要补充。
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