• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Advances of cancer therapy by nanotechnology.纳米技术在癌症治疗方面的进展。
Cancer Res Treat. 2009 Mar;41(1):1-11. doi: 10.4143/crt.2009.41.1.1. Epub 2009 Mar 31.
2
Nanobiotechnology-based drug delivery in brain targeting.基于纳米生物技术的脑靶向给药
Curr Pharm Biotechnol. 2013;14(15):1264-74. doi: 10.2174/1389201015666140608143719.
3
Nasal-nanotechnology: revolution for efficient therapeutics delivery.鼻腔纳米技术:高效治疗药物输送的革命。
Drug Deliv. 2016;23(3):681-93. doi: 10.3109/10717544.2014.920431. Epub 2014 Jun 5.
4
Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy.基于纳米技术的用于有效抗癌治疗的药物和制剂的最新见解。
J Nanobiotechnology. 2016 May 26;14(1):39. doi: 10.1186/s12951-016-0193-x.
5
Nanotechnology Assisted Chemotherapy for Targeted Cancer Treatment: Recent Advances and Clinical Perspectives.纳米技术辅助化疗用于靶向癌症治疗:最新进展和临床观点。
Curr Top Med Chem. 2020;20(27):2442-2458. doi: 10.2174/1568026620666200722110808.
6
Nanosize drug delivery system.纳米尺寸药物递送系统。
Curr Pharm Biotechnol. 2013;14(15):1221. doi: 10.2174/138920101415140804121008.
7
Stimuli-responsive nanoscale drug delivery systems for cancer therapy.刺激响应型纳米药物递送系统用于癌症治疗。
J Drug Target. 2019 Apr;27(4):423-433. doi: 10.1080/1061186X.2018.1519029. Epub 2019 Jan 24.
8
Application of nanotechnology in cancer therapy and imaging.纳米技术在癌症治疗与成像中的应用。
CA Cancer J Clin. 2008 Mar-Apr;58(2):97-110. doi: 10.3322/CA.2007.0003. Epub 2008 Jan 28.
9
Advances in Sub-Micron Particle Based Aerosol Strategies for Efficient Systemic Delivery of Therapeutic Agents.基于亚微米颗粒的气溶胶策略在治疗剂高效全身递送方面的进展。
Curr Pharm Des. 2016;22(17):2470-80. doi: 10.2174/1381612822666160225155637.
10
Broad overview of engineering of functional nanosystems for skin delivery.用于皮肤递药的功能纳米系统工程的广泛概述。
Int J Pharm. 2017 Nov 5;532(2):710-728. doi: 10.1016/j.ijpharm.2017.07.078. Epub 2017 Jul 29.

引用本文的文献

1
The role of HOXA1 in cancer and targeted therapy.HOXA1在癌症及靶向治疗中的作用。
Med Oncol. 2025 Aug 4;42(9):405. doi: 10.1007/s12032-025-02980-2.
2
Nanoparticles of banana peels as a potential source of bioactive compounds and their activities on HepG2.香蕉皮纳米颗粒作为生物活性化合物的潜在来源及其对肝癌细胞株HepG2的作用
Sci Rep. 2025 Apr 5;15(1):11721. doi: 10.1038/s41598-025-93382-x.
3
Recent Trends in Nanocarrier-Based Drug Delivery System for Prostate Cancer.基于纳米载体的药物传递系统治疗前列腺癌的最新研究进展。
AAPS PharmSciTech. 2024 Mar 6;25(3):55. doi: 10.1208/s12249-024-02765-2.
4
Extracellular vesicles and exosome-like nanovesicles as pioneering oral drug delivery systems.细胞外囊泡和外泌体样纳米囊泡作为开创性的口服给药系统。
Front Bioeng Biotechnol. 2024 Jan 8;11:1307878. doi: 10.3389/fbioe.2023.1307878. eCollection 2023.
5
Current status of Fe-based MOFs in biomedical applications.铁基金属有机框架材料在生物医学应用中的研究现状
RSC Med Chem. 2023 Sep 29;14(12):2473-2495. doi: 10.1039/d3md00416c. eCollection 2023 Dec 13.
6
Hybrid Nanoplatforms Comprising Organic Nanocompartments Encapsulating Inorganic Nanoparticles for Enhanced Drug Delivery and Bioimaging Applications.包含封装无机纳米粒子的有机纳米隔室的杂化纳米平台,用于增强药物传递和生物成像应用。
Molecules. 2023 Jul 27;28(15):5694. doi: 10.3390/molecules28155694.
7
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics.癌症化疗及其他:当前状况、候选药物、相关风险以及靶向治疗的进展。
Genes Dis. 2022 Mar 18;10(4):1367-1401. doi: 10.1016/j.gendis.2022.02.007. eCollection 2023 Jul.
8
Advanced Delivery System of Polyphenols for Effective Cancer Prevention and Therapy.用于有效预防和治疗癌症的多酚先进递送系统
Antioxidants (Basel). 2023 May 5;12(5):1048. doi: 10.3390/antiox12051048.
9
Approved Nanomedicine against Diseases.已批准的用于治疗疾病的纳米药物。
Pharmaceutics. 2023 Feb 26;15(3):774. doi: 10.3390/pharmaceutics15030774.
10
Functionalization of curcumin nanomedicines: a recent promising adaptation to maximize pharmacokinetic profile, specific cell internalization and anticancer efficacy against breast cancer.姜黄素纳米药物的功能化:一种最近有前途的适应策略,可最大限度地提高药代动力学特征、特定细胞内化和抗癌功效,以对抗乳腺癌。
J Nanobiotechnology. 2023 Mar 25;21(1):106. doi: 10.1186/s12951-023-01854-x.

本文引用的文献

1
Dendrimers: From Design to Application-A Progress Report.树枝状大分子:从设计到应用——进展报告
Angew Chem Int Ed Engl. 1999 Apr 1;38(7):884-905. doi: 10.1002/(SICI)1521-3773(19990401)38:7<884::AID-ANIE884>3.0.CO;2-K.
2
Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug.检测头颈部鳞状细胞癌中叶酸受体的表达,作为一种新型纳米治疗药物的靶点。
Head Neck. 2009 Apr;31(4):475-81. doi: 10.1002/hed.21003.
3
Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery.
Chem Commun (Camb). 2008 Dec 28(48):6570-2. doi: 10.1039/b815918a. Epub 2008 Nov 12.
4
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles.通过适配体功能化的铂(IV)前药-PLGA-PEG纳米颗粒将顺铂靶向递送至前列腺癌细胞。
Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17356-61. doi: 10.1073/pnas.0809154105. Epub 2008 Oct 31.
5
Nanoparticle therapeutics: an emerging treatment modality for cancer.纳米颗粒疗法:一种新兴的癌症治疗方式。
Nat Rev Drug Discov. 2008 Sep;7(9):771-82. doi: 10.1038/nrd2614.
6
The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line.不同纳米颗粒表面化学性质和尺寸对小鼠巨噬细胞系摄取及毒性的影响。
Toxicol Appl Pharmacol. 2008 Nov 1;232(3):418-27. doi: 10.1016/j.taap.2008.06.009. Epub 2008 Jul 1.
7
Highly efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer.用于癌症体内光动力治疗的金纳米颗粒载体高效药物递送
J Am Chem Soc. 2008 Aug 13;130(32):10643-7. doi: 10.1021/ja801631c. Epub 2008 Jul 22.
8
An orally delivered small-molecule formulation with antiangiogenic and anticancer activity.一种具有抗血管生成和抗癌活性的口服小分子制剂。
Nat Biotechnol. 2008 Jul;26(7):799-807. doi: 10.1038/nbt1415. Epub 2008 Jun 29.
9
Chemical design of nanoparticle probes for high-performance magnetic resonance imaging.用于高性能磁共振成像的纳米粒子探针的化学设计
Angew Chem Int Ed Engl. 2008;47(28):5122-35. doi: 10.1002/anie.200701674.
10
Magnetic nanoparticles in MR imaging and drug delivery.磁共振成像与药物递送中的磁性纳米颗粒。
Adv Drug Deliv Rev. 2008 Aug 17;60(11):1252-1265. doi: 10.1016/j.addr.2008.03.018. Epub 2008 Apr 10.

纳米技术在癌症治疗方面的进展。

Advances of cancer therapy by nanotechnology.

机构信息

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.

出版信息

Cancer Res Treat. 2009 Mar;41(1):1-11. doi: 10.4143/crt.2009.41.1.1. Epub 2009 Mar 31.

DOI:10.4143/crt.2009.41.1.1
PMID:19688065
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2699095/
Abstract

Recent developments in nanotechnology offer researchers opportunities to significantly transform cancer therapeutics. This technology has enabled the manipulation of the biological and physicochemical properties of nanomaterials to facilitate more efficient drug targeting and delivery. Clinical investigations suggest that therapeutic nanoparticles can enhance efficacy and reduced side effects compared with conventional cancer therapeutic drugs. Encouraged by rapid and promising progress in cancer nanotechnology, researchers continue to develop novel and efficacious nanoparticles for drug delivery. The use of therapeutic nanoparticles as unique drug delivery systems will be a significant addition to current cancer therapeutics.

摘要

纳米技术的最新发展为研究人员提供了重大改变癌症治疗方法的机会。这项技术使人们能够操纵纳米材料的生物和物理化学特性,以促进更有效的药物靶向和传递。临床研究表明,与传统的癌症治疗药物相比,治疗纳米粒子可以提高疗效并降低副作用。由于癌症纳米技术的快速和有希望的进展,研究人员继续开发用于药物输送的新型有效纳米粒子。治疗纳米粒子作为独特的药物输送系统的使用将是当前癌症治疗方法的重要补充。