全科医疗中长效苯二氮䓬类药物使用者特征的对照比较。
Controlled comparison of the characteristics of long-term benzodiazepine users in general practice.
作者信息
Simpson R J, Power K G, Wallace L A, Butcher M H, Swanson V, Simpson E C
机构信息
Forth Valley GP Research Group, University of Stirling.
出版信息
Br J Gen Pract. 1990 Jan;40(330):22-6.
From three general practices, served by 11 principals, 205 long-term benzodiazepine users were identified and matched for age and sex with controls. Benzodiazepine users had significantly higher rates of previous physical illness, consultation and non-psychotropic drug consumption than controls. The characteristics of those receiving prescriptions for benzodiazepine hypnotics alone, anxiolytics alone and anxiolytics plus hypnotics were also investigated. Significant differences emerged between these three groups. Patients receiving hypnotics only were older, had a history of more physical illness and had received more non-psychotropic medication than patients receiving anxiolytics only. The anxiolytic plus hypnotic group had previously received more hypnotics and were currently receiving more medication than the group receiving anxiolytics alone. The results are discussed in relation to current concerns about benzodiazepine dependence and withdrawal.
在由11位负责人提供服务的三家普通诊所中，识别出了205名长期使用苯二氮䓬类药物的患者，并按照年龄和性别与对照组进行了匹配。与对照组相比，苯二氮䓬类药物使用者既往身体疾病、就诊及非精神药物消费的发生率显著更高。还对仅接受苯二氮䓬类催眠药处方、仅接受抗焦虑药处方以及接受抗焦虑药加催眠药处方的患者的特征进行了调查。这三组之间出现了显著差异。仅接受催眠药治疗的患者比仅接受抗焦虑药治疗的患者年龄更大，有更多身体疾病史，并且接受了更多的非精神药物治疗。与仅接受抗焦虑药治疗的组相比，抗焦虑药加催眠药组既往接受过更多的催眠药治疗，目前服用的药物也更多。结合当前对苯二氮䓬类药物依赖和戒断的关注对结果进行了讨论。
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