气功对癌症患者生活质量、疲劳、情绪和炎症的影响：一项随机对照试验。
Impact of medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial.
机构信息
Department of Medicine, Concord Repatriation General Hospital, University of Sydney, Concord; Center for Medical Psychology and Evidence-based Decision-making, School of Psychology, University of Sydney; Sydney Cancer Center, Concord Repatriation General Hospital.
Center for Medical Psychology and Evidence-based Decision-making, School of Psychology, University of Sydney.
出版信息
Ann Oncol. 2010 Mar;21(3):608-614. doi: 10.1093/annonc/mdp479. Epub 2009 Oct 30.
BACKGROUND
Substantial numbers of cancer patients use complementary medicine therapies, even without a supportive evidence base. This study aimed to evaluate in a randomized controlled trial, the use of Medical Qigong (MQ) compared with usual care to improve the quality of life (QOL) of cancer patients.
PATIENTS AND METHODS
One hundred and sixty-two patients with a range of cancers were recruited. QOL and fatigue were measured by Functional Assessment of Cancer Therapy-General and Functional Assessment of Cancer Therapy-Fatigue, respectively, and mood status by Profile of Mood State. The inflammatory marker serum C-reactive protein (CRP) was monitored serially.
RESULTS
Regression analysis indicated that the MQ group significantly improved overall QOL (t(144) = -5.761, P < 0.001), fatigue (t(153) = -5.621, P < 0.001), mood disturbance (t(122) =2.346, P = 0.021) and inflammation (CRP) (t(99) = 2.042, P < 0.044) compared with usual care after controlling for baseline variables.
CONCLUSIONS
This study indicates that MQ can improve cancer patients' overall QOL and mood status and reduce specific side-effects of treatment. It may also produce physical benefits in the long term through reduced inflammation.
背景
大量癌症患者使用补充医学疗法，即使没有支持证据。本研究旨在通过随机对照试验评估气功（MQ）与常规护理相比，改善癌症患者生活质量（QOL）的效果。
患者和方法
招募了 162 名患有各种癌症的患者。使用癌症治疗功能评估-一般量表（FACT-G）和癌症治疗功能评估-疲劳量表（FACT-F）分别测量 QOL 和疲劳，使用心境状态量表（POMS）测量情绪状态。连续监测炎症标志物血清 C 反应蛋白（CRP）。
结果
回归分析表明，与常规护理相比，MQ 组在整体 QOL（t（144）=-5.761，P<0.001）、疲劳（t（153）=-5.621，P<0.001）、情绪障碍（t（122）=2.346，P=0.021）和炎症（CRP）（t（99）=2.042，P<0.044）方面均有显著改善，在控制基线变量后。
结论
本研究表明，MQ 可以改善癌症患者的整体 QOL 和情绪状态，减轻特定的治疗副作用。它还可能通过减少炎症在长期内产生身体上的益处。
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