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克劳斯·康拉德(1905-1961):妄想情绪、精神病和精神分裂症早期。

Klaus Conrad (1905-1961): delusional mood, psychosis, and beginning schizophrenia.

机构信息

Department of Psychiatry, Clinical Neuroscience Research Unit, Yale University School of Medicine, CMHC 339-A, 34 Park Street, New Haven, CT 06519, USA.

出版信息

Schizophr Bull. 2010 Jan;36(1):9-13. doi: 10.1093/schbul/sbp144. Epub 2009 Dec 4.

DOI:10.1093/schbul/sbp144
PMID:19965934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2800156/
Abstract

Klaus Conrad's major contribution to the phenomenology of psychosis focused on the patient's experiences during the prodromal and early psychotic phases of schizophrenia. The literature in English concerning his work is sparse, in part because Conrad's work contains complex concepts that lose much in translation. This communication attempts to clarify Conrad's thought, especially as it pertains to the role of mood and delusions in beginning psychosis and its underlying neurobiology.

摘要

克劳斯·康拉德对精神病学现象学的主要贡献集中在精神分裂症前驱期和早期精神病阶段患者的体验上。关于他的工作的英文文献很少,部分原因是康拉德的工作包含复杂的概念,在翻译中会丢失很多内容。本通讯试图澄清康拉德的思想,特别是他对情绪和妄想在开始出现精神病及其潜在神经生物学中的作用的看法。

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Schizophr Bull. 2010 Jan;36(1):9-13. doi: 10.1093/schbul/sbp144. Epub 2009 Dec 4.
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本文引用的文献

1
Kafka, paranoic doubles and the brain: hypnagogic vs. hyper-reflexive models of disrupted self in neuropsychiatric disorders and anomalous conscious states.卡夫卡、偏执型替身与大脑:神经精神疾病和异常意识状态中自我紊乱的入睡前与过度反射模型
Philos Ethics Humanit Med. 2010 Aug 20;5:13. doi: 10.1186/1747-5341-5-13.
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Why do delusions persist?妄想为何持续存在?
Front Hum Neurosci. 2009 Jul 10;3:12. doi: 10.3389/neuro.09.012.2009. eCollection 2009.
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Subjective symptoms of schizophrenia in research and the clinic: the basic symptom concept.研究与临床中精神分裂症的主观症状:基本症状概念
Schizophr Bull. 2009 Jan;35(1):5-8. doi: 10.1093/schbul/sbn139.
4
Missing links in phenomenological clinical neuroscience: why we still are not there yet.现象学临床神经科学中的缺失环节:为何我们仍未达成目标。
Curr Opin Psychiatry. 2007 Nov;20(6):559-69. doi: 10.1097/YCO.0b013e3282f128b8.
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Is minimal self preserved in schizophrenia? A subcomponents view.精神分裂症中最小自我是否得以保留?一种子成分观点。
Conscious Cogn. 2007 Sep;16(3):715-21. doi: 10.1016/j.concog.2007.07.009.
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Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions.精神病中预测误差信号的破坏:妄想联想解释的证据。
Brain. 2007 Sep;130(Pt 9):2387-400. doi: 10.1093/brain/awm173. Epub 2007 Aug 9.
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Substantia nigra/ventral tegmental reward prediction error disruption in psychosis.精神分裂症中黑质/腹侧被盖区奖励预测误差的破坏
Mol Psychiatry. 2008 Mar;13(3):239, 267-76. doi: 10.1038/sj.mp.4002058. Epub 2007 Aug 7.
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Jumping to delusions? Paranoia, probabilistic reasoning, and need for closure.急于陷入妄想?偏执、概率推理与认知闭合需求。
Cogn Neuropsychiatry. 2007 Jul;12(4):362-76. doi: 10.1080/13546800701203769.
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Perceptual anomalies in schizophrenia: integrating phenomenology and cognitive neuroscience.精神分裂症中的感知异常:整合现象学与认知神经科学
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Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, brain activity, and psychosis.学习过程中的额叶反应可预测对氯胺酮致精神病效应的易感性:连接认知、大脑活动和精神病。
Arch Gen Psychiatry. 2006 Jun;63(6):611-21. doi: 10.1001/archpsyc.63.6.611.