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7S RNA的基因在大肠杆菌生长过程中可取代4.5S RNA的基因。

Genes for 7S RNAs can replace the gene for 4.5S RNA in growth of Escherichia coli.

作者信息

Brown S

机构信息

Laboratory of Chromosome Biology, National Cancer Institute-Frederick Cancer Research and Development Center, Maryland 21702.

出版信息

J Bacteriol. 1991 Mar;173(5):1835-7. doi: 10.1128/jb.173.5.1835-1837.1991.

DOI:10.1128/jb.173.5.1835-1837.1991
PMID:1999396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC207341/
Abstract

4.5S RNAs of eubacteria and 7S RNAs of archaebacteria and eukaryotes exist in a hairpin conformation. The apex of this hairpin displays structural and sequence similarities among both 4.5S and 7S RNAs. Furthermore, a hyphenated sequence of 16 nucleotides is conserved in all eubacterial 4.5S RNAs examined. In this article I report that 7S RNAs that contain this 16-nucleotide sequence are able to replace 4.5S RNAs and permit growth of Escherichia coli.

摘要

真细菌的4.5S RNA以及古细菌和真核生物的7S RNA以发夹构象存在。这种发夹的顶端在4.5S和7S RNA中都显示出结构和序列上的相似性。此外，在所检测的所有真细菌4.5S RNA中，一个16个核苷酸的连字符序列是保守的。在本文中，我报告称含有这个16个核苷酸序列的7S RNA能够替代4.5S RNA并使大肠杆菌生长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/207341/589bd94b97c4/jbacter00095-0278-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/207341/589bd94b97c4/jbacter00095-0278-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/207341/589bd94b97c4/jbacter00095-0278-a.jpg

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