Department of Surgery, University of Cincinnati Medical Center, PO Box 670558, 231 Albert Sabin Way, Cincinnati OH 45267-0558, USA.
Respir Care. 2010 Feb;55(2):209-16; discussion 216.
Noninvasive ventilation (NIV) is a standard of care for the treatment of exacerbation of chronic obstructive pulmonary disease, to prevent intubation and reduce morbidity and mortality. The need for humidification of NIV gas is controversial. Some unique aspects of NIV conspire to alter the delivered humidity and airway function. In the presence of air leaks, unidirectional air flow dries the airways and increases airway resistance. Patient comfort is also a critical issue, as tolerance of NIV is often tied to patient comfort. This paper provides the arguments for and against routine humidification during NIV in the hospital setting. Data from clinical research demonstrate the effects of delivered humidification on relevant physiologic variables. The impact of humidification on NIV success/failure remains speculative.
无创通气（NIV）是治疗慢性阻塞性肺疾病加重的标准治疗方法，可预防插管并降低发病率和死亡率。NIV 气体加湿的必要性存在争议。NIV 的一些独特方面会改变输送的湿度和气道功能。在存在空气泄漏的情况下，单向气流会使气道变干并增加气道阻力。患者舒适度也是一个关键问题，因为对 NIV 的耐受性通常与患者舒适度有关。本文提供了在医院环境中进行 NIV 时常规加湿的正反两方面论点。临床研究中的数据表明了输送加湿对相关生理变量的影响。加湿对 NIV 成功/失败的影响仍在推测之中。
