Sathvik B S, Parthasarathi G, Narahari M G, Gurudev K C
Department of Pharmacy Practice, J.S.S. College of Pharmacy, Mysore - 570 015, India.
Indian J Nephrol. 2008 Oct;18(4):141-9. doi: 10.4103/0971-4065.45288.
A cross-sectional study was conducted to evaluate the quality of life (QOL) of hemodialysis patients. An attempt was made to compare the QOL of hemodialysis patients with the QOL of the general population, renal transplant patients, and patients with a chronic disease, in this case, asthma. The WHOQOL-BREF questionnaire was used to assess the quality of life. Hemodialysis patients who had completed three months of maintenance hemodialysis (n = 75) were enrolled into the study. The quality of life of hemodialysis patients was found to be significantly impaired (P < 0.05) in comparison to healthy individuals of the general population, particularly with respect to the physical, psychological, and social relationship domains. In comparison to the quality of life of renal transplant patients, the quality of life of hemodialysis patients was significantly (P < 0.05) lower in all the four WHOQOL-BREF domains. Only in the environmental dimension was the quality of life of hemodialysis patients found to be significantly lower than that of the asthma patients. Female hemodialysis patients showed significantly (P < 0.05) lower quality of life than did male patients in the psychological and environmental dimensions of WHOQOL-BREF. A positive association was seen between higher education and the psychological functioning and the environmental dimensions of WHOQOL-BREF. Thus, the quality of life of hemodialysis patients was found to be considerably impaired when compared to that of healthy individuals of the general population as well as of renal transplant patients.
开展了一项横断面研究以评估血液透析患者的生活质量（QOL）。尝试将血液透析患者的生活质量与普通人群、肾移植患者以及慢性病（此例为哮喘）患者的生活质量进行比较。使用世界卫生组织生活质量简表（WHOQOL - BREF）问卷来评估生活质量。完成三个月维持性血液透析的血液透析患者（n = 75）被纳入研究。结果发现，与普通人群中的健康个体相比，血液透析患者的生活质量显著受损（P < 0.05），尤其是在身体、心理和社会关系领域。与肾移植患者的生活质量相比，血液透析患者在WHOQOL - BREF的所有四个领域的生活质量均显著更低（P < 0.05）。仅在环境维度上，发现血液透析患者的生活质量显著低于哮喘患者。在WHOQOL - BREF的心理和环境维度上，女性血液透析患者的生活质量显著低于男性患者（P < 0.05）。在高等教育与WHOQOL - BREF的心理功能及环境维度之间发现了正相关关系。因此，与普通人群中的健康个体以及肾移植患者相比，血液透析患者的生活质量被发现受到了相当大的损害。
