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Consilience of rodent and human phenotypes relevant for alcohol dependence.与酒精依赖相关的啮齿动物和人类表型的一致性。
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Human and laboratory rodent low response to alcohol: is better consilience possible?人类和实验用鼠类对酒精的低反应性：是否可能更好地达成一致？
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Ethanol consumption: how should we measure it? Achieving consilience between human and animal phenotypes.乙醇摄入：我们应该如何测量它？在人类和动物表型之间实现一致。
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Sweet liking and high novelty seeking: independent phenotypes associated with alcohol-related problems.喜欢甜食和追求新奇：与酒精相关问题相关的独立表型。
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Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits.Y染色体对酒精依赖及相关人格特质影响的分支关联分析
Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4204-9. doi: 10.1073/pnas.96.7.4204.
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Characterization of an alcohol addiction-prone phenotype in mice.酒精成瘾倾向表型在小鼠中的特征。
Addict Biol. 2012 May;17(3):601-12. doi: 10.1111/j.1369-1600.2011.00394.x. Epub 2011 Oct 21.
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Novelty seeking as a moderator of familial risk for alcohol dependence.寻求新奇作为酒精依赖家族风险的调节因素。
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Association of VMAT2 gene polymorphisms with alcohol dependence.VMAT2 基因多态性与酒精依赖的关联。
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Sub-dimensions of Alcohol Use Disorder in Alcohol Preferring and Non-preferring Rats, a Comparative Study.酒精偏好和非偏好大鼠酒精使用障碍的子维度：一项比较研究
Front Behav Neurosci. 2019 Jan 30;13:3. doi: 10.3389/fnbeh.2019.00003. eCollection 2019.
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Frequency of alcohol consumption in humans; the role of metabotropic glutamate receptors and downstream signaling pathways.人类酒精消费频率；代谢型谷氨酸受体及下游信号通路的作用。
Transl Psychiatry. 2015 Jun 23;5(6):e586. doi: 10.1038/tp.2015.70.
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A targeted review of the neurobiology and genetics of behavioural addictions: an emerging area of research.行为成瘾的神经生物学和遗传学的针对性综述：一个新兴的研究领域。
Can J Psychiatry. 2013 May;58(5):260-73. doi: 10.1177/070674371305800503.
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Bridging Animal and Human Models: Translating From (and to) Animal Genetics.连接动物模型与人类模型：从动物遗传学（及向动物遗传学）进行转化
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The genetics of addiction-a translational perspective.成瘾的遗传学研究——转化视角
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Chronic free-choice drinking in crossed high alcohol preferring mice leads to sustained blood ethanol levels and metabolic tolerance without evidence of liver damage.慢性自由选择饮酒的交叉高酒精偏好小鼠导致持续的血液乙醇水平和代谢耐受，没有肝损伤的证据。
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Impaired control over alcohol use: An under-addressed risk factor for problem drinking in young adults?酒精使用控制受损：年轻人问题饮酒的一个未充分关注的风险因素？
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Pharmacologically relevant intake during chronic, free-choice drinking rhythms in selectively bred high alcohol-preferring mice.在选择性繁殖的高酒精偏好小鼠的慢性、自由选择饮酒节律中，药物相关的摄入。
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Modeling the diagnostic criteria for alcohol dependence with genetic animal models.利用遗传动物模型模拟酒精依赖的诊断标准。
Curr Top Behav Neurosci. 2013;13:187-221. doi: 10.1007/7854_2011_162.
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Behavioral profiling of multiple pairs of rats selectively bred for high and low alcohol intake using the MCSF test.采用 MCSF 测试对高、低酒精摄入量的大鼠进行多对选择繁殖的行为分析。
Addict Biol. 2012 Jan;17(1):33-46. doi: 10.1111/j.1369-1600.2011.00327.x. Epub 2011 Apr 26.

本文引用的文献

1
A line of mice selected for high blood ethanol concentrations shows drinking in the dark to intoxication.一组因血液乙醇浓度高而被选育的小鼠表现出在黑暗中饮酒直至醉酒。
Biol Psychiatry. 2009 Apr 15;65(8):662-70. doi: 10.1016/j.biopsych.2008.11.002. Epub 2008 Dec 18.
2
Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of high-alcohol-drinking (HAD) rats.同时接触多种乙醇浓度和反复剥夺对高饮酒量（HAD）大鼠酒精摄入量的影响。
Addict Biol. 2009 Apr;14(2):152-64. doi: 10.1111/j.1369-1600.2008.00140.x. Epub 2008 Dec 12.
3
Detection of reciprocal quantitative trait loci for acute ethanol withdrawal and ethanol consumption in heterogeneous stock mice.在异质种群小鼠中检测急性乙醇戒断和乙醇消耗的相互数量性状基因座。
Psychopharmacology (Berl). 2009 May;203(4):713-22. doi: 10.1007/s00213-008-1418-y. Epub 2008 Dec 4.
4
Review. Neurogenetic studies of alcohol addiction.综述：酒精成瘾的神经遗传学研究
Philos Trans R Soc Lond B Biol Sci. 2008 Oct 12;363(1507):3201-11. doi: 10.1098/rstb.2008.0101.
5
The genomic determinants of alcohol preference in mice.小鼠酒精偏好的基因组决定因素。
Mamm Genome. 2008 May;19(5):352-65. doi: 10.1007/s00335-008-9115-z. Epub 2008 Jun 19.
6
Genetic and environmental influences on alcohol, caffeine, cannabis, and nicotine use from early adolescence to middle adulthood.从青春期早期到中年期，遗传和环境因素对酒精、咖啡因、大麻和尼古丁使用的影响。
Arch Gen Psychiatry. 2008 Jun;65(6):674-82. doi: 10.1001/archpsyc.65.6.674.
7
Brain chromatin remodeling: a novel mechanism of alcoholism.脑染色质重塑：酒精中毒的一种新机制。
J Neurosci. 2008 Apr 2;28(14):3729-37. doi: 10.1523/JNEUROSCI.5731-07.2008.
8
Genetic factors influencing alcohol dependence.影响酒精依赖的遗传因素。
Br J Pharmacol. 2008 May;154(2):275-87. doi: 10.1038/bjp.2008.88. Epub 2008 Mar 24.
9
Neuropharmacology of alcohol addiction.酒精成瘾的神经药理学
Br J Pharmacol. 2008 May;154(2):299-315. doi: 10.1038/bjp.2008.30. Epub 2008 Mar 3.
10
Ethanol drinking in rodents: is free-choice drinking related to the reinforcing effects of ethanol?啮齿动物中的乙醇摄入：自由选择饮酒与乙醇的强化作用有关吗？
Alcohol. 2008 Feb;42(1):1-11. doi: 10.1016/j.alcohol.2007.10.005.

Consilience of rodent and human phenotypes relevant for alcohol dependence.

作者信息

Crabbe John C

出版信息

Addict Biol. 2010 Apr;15(2):103-8. doi: 10.1111/j.1369-1600.2009.00188.x.

DOI:10.1111/j.1369-1600.2009.00188.x
PMID:20148774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2853473/
Abstract
摘要