Kisangau D P, Hosea K M, Joseph C C, Lyaruu H V M
Department of Botany, University of Dar es Salaam, P.O. Box 35060, Dar es Salaam, Tanzania.
Afr J Tradit Complement Altern Med. 2007 Jun 10;4(4):510-23. doi: 10.4314/ajtcam.v4i4.31245.
Plants used in traditional medicine in Bukoba Rural district in Tanzania were evaluated for their in vitro antimicrobial activities. Plant materials from eight plant species (Harungana madagascariensis (Lam) Poir., Jatropha curcas L., Lantana trifolia L., Plectranthus barbatus Andr., Pseudospondias microcarpa Engl., Psorospermum febrifugum Spach, Teclea nobilis Del. and Vernonia adoensis [Warp.] SL) were collected based on ethnomedical information provided by traditional herbal practitioners. Results of the study indicate that extracts from the eight plant species were active against at least one or more of the test organisms (Bacillus subtilis, Staphylococcus aureus [gram positive], Escherichia coli, Pseudomonas aeruginosa [gram negative] and Candida albicans [Yeast]). A profile of secondary metabolites (alkaloids, terpenoids, triterpenes, phenolics, tannins, flavonoids, anthraquinones, flavonols/flavones and /or chalcones, sterols and saponins) was obtained for three plant species (Jatropha curcas L., Plectranthus barbatus Andr., and Pseudospondias microcarpa Engl.). The paper discusses the probable therapeutic basis of these traditional plants based on their secondary metabolite profiles and for the first time draws research attention to Bukoba Rural district as a source for plants with potential pharmaceutical applications.
对坦桑尼亚布科巴农村地区传统医学中使用的植物进行了体外抗菌活性评估。根据传统草药从业者提供的民族医学信息，采集了来自8种植物（马达加斯加哈伦加那木（Lam）Poir.、麻疯树、三裂叶马缨丹、毛喉鞘蕊花、小叶假槟榔青、退热假虎刺、高贵泰氏木和阿多尼斑鸠菊[Warp.]SL）的植物材料。研究结果表明，这8种植物的提取物对至少一种或多种受试生物（枯草芽孢杆菌、金黄色葡萄球菌[革兰氏阳性]、大肠杆菌、铜绿假单胞菌[革兰氏阴性]和白色念珠菌[酵母]）具有活性。获得了三种植物（麻疯树、毛喉鞘蕊花和小叶假槟榔青）的次生代谢产物（生物碱、萜类化合物、三萜类化合物、酚类化合物、单宁、黄酮类化合物、蒽醌类化合物、黄酮醇/黄酮和/或查耳酮、甾醇和皂苷）概况。本文根据这些传统植物的次生代谢产物概况讨论了其可能的治疗基础，并首次将研究注意力吸引到布科巴农村地区，将其作为具有潜在药用价值植物的来源。
