Pavan Stefano, Jacobsen Evert, Visser Richard G F, Bai Yuling
Mol Breed. 2010 Jan;25(1):1-12. doi: 10.1007/s11032-009-9323-6. Epub 2009 Aug 15.
Recent studies on plant immunity have suggested that a pathogen should suppress induced plant defense in order to infect a plant species, which otherwise would have been a nonhost to the pathogen. For this purpose, pathogens exploit effector molecules to interfere with different layers of plant defense responses. In this review, we summarize the latest findings on plant factors that are activated by pathogen effectors to suppress plant immunity. By looking from a different point of view into host and nonhost resistance, we propose a novel breeding strategy: disabling plant disease susceptibility genes (S-genes) to achieve durable and broad-spectrum resistance.
近期关于植物免疫的研究表明，病原体为了侵染一种植物物种，应该抑制植物的诱导防御反应，否则该植物物种对病原体来说就是非寄主。为此，病原体利用效应分子干扰植物防御反应的不同层面。在本综述中，我们总结了病原体效应分子激活以抑制植物免疫的植物因子的最新研究结果。从不同角度审视寄主和非寄主抗性，我们提出了一种新的育种策略：使植物感病基因（S基因）失活，以实现持久和广谱抗性。
