Matthew C A, Moore M J
Orthopaedic Research Unit, University of Cambridge Clinical School, Addenbrookes Hospital.
J Anat. 1991 Apr;175:263-8.
The regenerative potential of completely transected tendon has been assessed in rat extensor tendon. Collagen fibril diameter distributions were calculated within the gap region of the healing tissue at 10, 30, 60, 120 and 240 days postoperatively. At each age the distribution was found to be unimodal with no indication of any return of bimodality. These results suggest that mechanical stimuli may be a controlling factor in determining fibril diameters and that mature tendon may be unable to reproduce a bimodal collagen fibril diameter distribution subsequent to trauma.
已在大鼠伸肌腱中评估了完全横断肌腱的再生潜力。计算了术后10天、30天、60天、120天和240天愈合组织间隙区域内的胶原纤维直径分布。在每个时间点，发现分布均为单峰，没有任何双峰回归的迹象。这些结果表明，机械刺激可能是决定纤维直径的控制因素，并且成熟肌腱在创伤后可能无法再现双峰胶原纤维直径分布。
