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纳米技术在干细胞中的进展与展望。

Advances and prospect of nanotechnology in stem cells.

机构信息

Department of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai, 200240, China.

出版信息

Nanoscale Res Lett. 2009 Mar 21;4(7):593-605. doi: 10.1007/s11671-009-9292-z.

DOI:10.1007/s11671-009-9292-z
PMID:20596412
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2894000/
Abstract

In recent years, stem cell nanotechnology has emerged as a new exciting field. Theoretical and experimental studies of interaction between nanomaterials or nanostructures and stem cells have made great advances. The importance of nanomaterials, nanostructures, and nanotechnology to the fundamental developments in stem cells-based therapies for injuries and degenerative diseases has been recognized. In particular, the effects of structure and properties of nanomaterials on the proliferation and differentiation of stem cells have become a new interdisciplinary frontier in regeneration medicine and material science. Here we review some of the main advances in this field over the past few years, explore the application prospects, and discuss the issues, approaches and challenges, with the aim of improving application of nanotechnology in the stem cells research and development.

摘要

近年来，干细胞纳米技术已成为一个令人兴奋的新领域。纳米材料或纳米结构与干细胞之间相互作用的理论和实验研究已经取得了重大进展。纳米材料、纳米结构和纳米技术对基于干细胞的治疗损伤和退行性疾病的基础发展的重要性已经得到了认可。特别是，纳米材料的结构和性能对干细胞的增殖和分化的影响已成为再生医学和材料科学的一个新的交叉前沿领域。在这里，我们回顾了过去几年这一领域的一些主要进展，探讨了其应用前景，并讨论了相关问题、方法和挑战，旨在提高纳米技术在干细胞研究与开发中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/da5542329032/1556-276X-4-593-8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/a85fb3ab9f4d/1556-276X-4-593-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/ed1ac772e2e9/1556-276X-4-593-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/4734b476c3f4/1556-276X-4-593-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/32014f9fa6e7/1556-276X-4-593-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/f8e4cbbf48e9/1556-276X-4-593-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/f32effc7519d/1556-276X-4-593-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/96aacd219453/1556-276X-4-593-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/da5542329032/1556-276X-4-593-8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/a85fb3ab9f4d/1556-276X-4-593-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/ed1ac772e2e9/1556-276X-4-593-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/4734b476c3f4/1556-276X-4-593-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/32014f9fa6e7/1556-276X-4-593-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/f8e4cbbf48e9/1556-276X-4-593-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/f32effc7519d/1556-276X-4-593-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/96aacd219453/1556-276X-4-593-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/449a/3243417/da5542329032/1556-276X-4-593-8.jpg

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本文引用的文献

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Nanotechnology for regenerative medicine: nanomaterials for stem cell imaging.

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Stem Cells Dev. 2008-6

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