健康犬的临床皮肤是犬乳头瘤病毒的潜在储库。
Clinically healthy skin of dogs is a potential reservoir for canine papillomaviruses.
机构信息
Dermatology Department, Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland.
出版信息
J Clin Microbiol. 2011 Feb;49(2):707-9. doi: 10.1128/JCM.02047-10. Epub 2010 Dec 15.
Abstract
Papillomaviruses have been linked to several skin disorders in the dog. In order to have a suitable diagnostic tool for canine papillomavirus detection, eight PCRs with published primer combinations were evaluated. The most sensitive PCR was used to demonstrate that papillomavirus DNA can be detected on nonlesional skin of dogs.
摘要
乳头瘤病毒与犬的几种皮肤疾病有关。为了有一个合适的犬乳头瘤病毒检测诊断工具，评估了 8 个具有已发表引物组合的 PCR。最敏感的 PCR 被用于证明可以在犬的非病变皮肤上检测到乳头瘤病毒 DNA。
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本文引用的文献
1
Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments.基于 189 种 HPV 型别对乳头瘤病毒（PVs）的分类以及分类学修订建议。
Virology. 2010 May 25;401(1):70-9. doi: 10.1016/j.virol.2010.02.002. Epub 2010 Mar 5.
2
Frequent detection of papillomavirus DNA in clinically normal skin of cats infected and noninfected with feline immunodeficiency virus.在感染和未感染猫免疫缺陷病毒的猫的临床正常皮肤中频繁检测到乳头瘤病毒DNA。
Vet Dermatol. 2010 Jun;21(3):307-10. doi: 10.1111/j.1365-3164.2009.00811.x. Epub 2009 Dec 23.
3
Canine inverted papillomas associated with DNA of four different papillomaviruses.犬倒置乳头状瘤与四种不同乳头瘤病毒的DNA相关。
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Clin Vaccine Immunol. 2009 Jan;16(1):66-72. doi: 10.1128/CVI.00346-08. Epub 2008 Nov 26.
6
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8
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10
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