重审查氨甲基三氟硼酸盐及其在 Suzuki-Miyaura 交叉偶联反应中的应用。
Reinvestigation of aminomethyltrifluoroborates and their application in Suzuki-Miyaura cross-coupling reactions.
机构信息
Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.
出版信息
J Org Chem. 2011 Apr 15;76(8):2762-9. doi: 10.1021/jo2001066. Epub 2011 Mar 15.
Abstract
A reinvestigation into the chemical composition of potassium aminomethyltrifluoroborates is reported. These trifluoroborato salts have been reassigned as zwitterionic ammoniomethyltrifluoroborates. Minor adjustments to the previously disclosed reaction conditions are reported that permit a similar level of activity as nucleophiles in Suzuki-Miyaura cross-coupling reactions.
摘要
重新研究了氨基甲基三氟硼酸钾的化学组成。这些三氟硼酸盐已被重新分配为两性离子氨甲基三氟硼酸盐。报告了对先前公开的反应条件的一些小的调整，这些调整使得它们在铃木-宫浦偶联反应中作为亲核试剂具有类似的活性水平。
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