促进垂序商陆花化学成分在 3T3-L1 细胞脂肪生成中的作用。
Promoting the effect of chemical constituents from the flowers of Poacynum hendersonii on adipogenesis in 3T3-L1 cells.
机构信息
Pharmaceutical Research and Technology Institute, Kinki University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
出版信息
J Nat Med. 2012 Jan;66(1):39-48. doi: 10.1007/s11418-011-0549-3. Epub 2011 Jun 7.
A novel sugar ester poacynose (1) was isolated from the flowers of Poacynum hendersonii together with 31 known compounds. The structure of 1 was established mainly on the basis of 1D and 2D NMR spectral data. Among the isolates, several constituents, such as kaempferol 3-O-sophoroside (5), picein (16), and 4-hydroxybenzoic acid 4-O-β-D-glucopyranoside (17) moderately promoted adipogenesis of 3T3-L1 cells. In addition, simultaneous quantitative analysis of eight flavonoid constituents from the flower and leaf parts of P. hendersonii was developed.
从麻叶钩藤（Poacynum hendersonii）的花朵中分离得到了一种新的糖酯化合物钩藤糖酯（1），并与 31 种已知化合物一起进行了研究。1 的结构主要是基于 1D 和 2D NMR 光谱数据确定的。在所分离的化合物中，一些成分，如山奈酚 3-O-槐糖苷（5）、白皮杉醇（16）和 4-羟基苯甲酸 4-O-β-D-吡喃葡萄糖苷（17），适度促进了 3T3-L1 细胞的脂肪生成。此外，还开发了同时定量分析麻叶钩藤花和叶部分的八种类黄酮成分的方法。
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