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萨尔兹曼番荔枝和皮氏番荔枝(番荔枝科)精油的化学成分、抗氧化、抗菌和杀幼虫活性

Chemical composition and antioxidant, antimicrobial, and larvicidal activities of the essential oils of Annona salzmannii and A. pickelii (Annonaceae).

作者信息

Costa Emmanoel Vilaça, Dutra Lívia Macedo, de Jesus Hugo César Ramos, Nogueira Paulo Cesar de Lima, Moraes Valéria Regina de Souza, Salvador Marcos José, Cavalcanti Sócrates Cabral de Holanda, dos Santos Roseli La Corte, Prata Ana Paula do Nacimento

机构信息

Laboratório de Pesquisa em Química Orgânica de Sergipe (LABORGANICS), Departamento de Química, Universidade Federal de Sergipe, CEP 49100-000, São Cristóvão, Sergipe, Brazil.

出版信息

Nat Prod Commun. 2011 Jun;6(6):907-12.

PMID:21815437
Abstract

The essential oils from the leaves of Annona salzmannii and A. pickelii (Annonaceae) growing in Sergipe, northeastern region of Brazil, were obtained by hydrodistillation using a Clevenger-type apparatus, and analyzed by GC/MS and GC/FID. Thirty-four compounds were identified in the essential oil of A. salzmannii and twenty-seven in that of A. pickelii; sesquiterpenes predominated in both essential oils. Bicyclogermacrene (20.3%), (E)-caryophyllene (19.9%), delta-cadinene (15.3%), alpha-copaene (10.0%), and allo-aromadendrene (5.7%) were the main components of A. salzmannii, and bicyclogermacrene (45.4%), (E)-caryophyllene (14.6%), and alpha-copaene (10.6%) of A. pickelii. The essential oils showed significant antioxidant capacity in the ORAC(FL) and DPPH assays. The antimicrobial activity of these essential oils was also evaluated against bacteria and fungi, as well as the larvicidal activity against Aedes aegypti larvae.

摘要

从生长在巴西东北部塞尔希培州的萨尔兹曼番荔枝(Annona salzmannii)和皮氏番荔枝(A. pickelii)(番荔枝科)叶片中提取的精油,采用克利夫兰式装置通过水蒸馏法获得,并通过气相色谱/质谱联用仪(GC/MS)和气相色谱/氢火焰离子化检测器(GC/FID)进行分析。在萨尔兹曼番荔枝精油中鉴定出34种化合物,在皮氏番荔枝精油中鉴定出27种化合物;两种精油中均以倍半萜类为主。双环大根香叶烯(20.3%)、(E)-石竹烯(19.9%)、δ-杜松烯(15.3%)、α-可巴烯(10.0%)和别香橙烯(5.7%)是萨尔兹曼番荔枝的主要成分,双环大根香叶烯(45.4%)、(E)-石竹烯(14.6%)和α-可巴烯(10.6%)是皮氏番荔枝的主要成分。这些精油在氧自由基吸收能力(ORAC(FL))和二苯基苦味酰基自由基(DPPH)测定中表现出显著的抗氧化能力。还评估了这些精油对细菌和真菌的抗菌活性,以及对埃及伊蚊幼虫的杀幼虫活性。

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