Department of Animal Production, Faculty of Veterinary Science, University of Murcia, Spain.
Vet Parasitol. 2012 Apr 30;185(2-4):158-63. doi: 10.1016/j.vetpar.2011.09.024. Epub 2011 Sep 22.
Coccidiostats could be phased out as feed additives before 1 January 2013 for public health and food safety reasons, and, as a replacement, bioactive compounds found in plants are currently being investigated since they are more likely to be found acceptable by consumers. The aim of our study was to evaluate the effect of cinnamaldehyde (CIN) and Echinacea purpurea plant extract (EP) as additives by analyzing the performance traits, oocyst excretion and intestinal lesions following experimental infection with Eimeria acervulina. A total of 72 Ross male broilers were raised from 1 to 35 d and randomly assigned to four dietary treatments: control, without additives (C); 150 mg kg(-1) cinnamaldehyde (CIN); 1000 mg kg(-1)E. purpurea plant extract (EP); 150 mg kg(-1) cinnamaldehyde plus 1000 mg kg(-1)E. purpurea plant extract (CIN+EP). At 25 d, 12 chickens per treatment were orally infected with E. acervulina. Coccidia infestation led to lower performance but with no significant differences between the infected groups. Oocyst output reached its peak from 6 to 9 d post-infection in all treatments. At duodenal level, gross lesion scores were lower for cinnamaldehyde diets (P<0.05). A similar trend was observed in the microscopic lesion scores, with a non-significant reduction as a result of cinnamaldehyde addition (P>0.05). Scoring methods for macro- and microscopic lesions showed a positive linear relationship (G=+0.70). Further studies are necessary to assess the possible anticoccidian action of the cinnamaldehyde and its value as an alternative or adjunct in therapeutic or prophylactic strategies.
出于公共健康和食品安全的原因，球虫抑制剂可能会在 2013 年 1 月 1 日之前被淘汰作为饲料添加剂，作为替代品，目前正在研究植物中的生物活性化合物，因为它们更有可能被消费者接受。我们的研究目的是评估肉桂醛（CIN）和松果菊提取物（EP）作为添加剂的效果，通过分析在感染堆形艾美耳球虫后鸡的生产性能、卵囊排泄和肠道病变。72 只罗斯雄性肉鸡从 1 日龄饲养到 35 日龄，随机分为 4 个日粮处理组：对照组，不添加任何添加剂（C）；150mg/kg 肉桂醛（CIN）；1000mg/kg 松果菊提取物（EP）；150mg/kg 肉桂醛加 1000mg/kg 松果菊提取物（CIN+EP）。在 25 日龄时，每组 12 只鸡经口感染堆形艾美耳球虫。球虫感染导致生产性能下降，但感染组之间没有显著差异。所有处理组的卵囊产量从感染后第 6 天到第 9 天达到峰值。在十二指肠水平，肉桂醛日粮的大体病变评分较低（P<0.05）。微观病变评分也出现了类似的趋势，肉桂醛的添加导致病变评分略有降低（P>0.05）。宏观和微观病变评分方法显示出正线性关系（G=+0.70）。需要进一步的研究来评估肉桂醛的抗球虫作用及其作为治疗或预防策略的替代或辅助药物的价值。
