National Mycobacterium Reference Laboratory, Health Protection Agency, London, United Kingdom.
J Clin Microbiol. 2012 Jan;50(1):164-5. doi: 10.1128/JCM.05692-11. Epub 2011 Nov 9.
Variable-number tandem repeat (VNTR) and spoligotyping analyses were used to assess transmission of Mycobacterium bovis between humans. VNTR was more discriminatory than spoligotyping. Low case numbers, despite a substantial animal reservoir, and resolution of all isolates provided no evidence of recent human-to-human transmission or recent significant infection from animals.
采用可变数目串联重复(VNTR)和 spoligotyping 分析来评估牛分枝杆菌在人与人之间的传播。VNTR 比 spoligotyping 更具区分度。尽管动物储存量很大,但由于病例数量少,且所有分离株均得到解决,因此没有证据表明最近存在人与人之间的传播或最近从动物感染的重大感染。