维甲酸：关于其在治疗痤疮中抗炎特性的综述
Tretinoin: A Review of Its Anti-inflammatory Properties in the Treatment of Acne.
作者信息
Schmidt Nicholas, Gans Eugene H
机构信息
Medicis Pharmaceutical Corporation, Scottsdale, Arizona.
出版信息
J Clin Aesthet Dermatol. 2011 Nov;4(11):22-9.
Abstract
Tretinoin has been primarily used for the early stages of acne because of its proven comedolytic end benefits. This article reviews and updates the collective body of evidence of tretinoin in the treatment of acne, which suggests that this drug also possesses a broad range of acne-related immunomodulating properties that are capable of disrupting and hindering the various stages of the inflammatory cascade and the production of proinflammatory factors associated with it.
摘要
由于维甲酸已被证实具有溶解粉刺的最终益处，它主要用于痤疮的早期阶段。本文回顾并更新了维甲酸治疗痤疮的相关证据，这些证据表明该药物还具有广泛的与痤疮相关的免疫调节特性，能够破坏和阻碍炎症级联反应的各个阶段以及与之相关的促炎因子的产生。
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