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Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats.长春花提取物对四氧嘧啶诱导糖尿病大鼠的降血糖活性。
Int J Endocrinol. 2010;2010:841090. doi: 10.1155/2010/841090. Epub 2010 Jun 22.
2
Antidiabetic, antihyperlipidemic and antioxidant activities of methanolic extract of Amaranthus viridis Linn in alloxan induced diabetic rats.绿穗苋甲醇提取物对四氧嘧啶诱导的糖尿病大鼠的抗糖尿病、抗高血脂和抗氧化活性
Exp Toxicol Pathol. 2012 Jan;64(1-2):75-9. doi: 10.1016/j.etp.2010.06.009. Epub 2010 Jul 18.
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[HbA1c, standardization and expression of results].
Endocrinol Nutr. 2010 May;57(5):177-81. doi: 10.1016/j.endonu.2010.02.010. Epub 2010 Apr 28.
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Antioxidant potential of aqueous extract of Phyllanthus amarus in rats.叶下珠水提物的抗氧化潜力。
Indian J Pharmacol. 2009 Apr;41(2):64-7. doi: 10.4103/0253-7613.51342.
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Lipid abnormalities in streptozotocin-diabetes: Amelioration by Morus indica L. cv Suguna leaves.链脲佐菌素诱导糖尿病中的脂质异常：桑（Morus indica L. cv Suguna）叶的改善作用。
Int J Diabetes Dev Ctries. 2009 Jul;29(3):123-8. doi: 10.4103/0973-3930.54289.
6
Serum uric acid levels predict the development of albuminuria over 6 years in patients with type 1 diabetes: findings from the Coronary Artery Calcification in Type 1 Diabetes study.血清尿酸水平可预测 1 型糖尿病患者 6 年内白蛋白尿的发展：来自 1 型糖尿病冠状动脉钙化研究的结果。
Nephrol Dial Transplant. 2010 Jun;25(6):1865-9. doi: 10.1093/ndt/gfp740. Epub 2010 Jan 11.
7
Antidiabetic activity of ethanolic extract of Zaleya decandra in alloxan-induced diabetic rats.千层塔正丁醇提取物对四氧嘧啶诱导糖尿病大鼠的降血糖作用。
Appl Biochem Biotechnol. 2010 Oct;162(4):1153-9. doi: 10.1007/s12010-009-8871-x. Epub 2009 Dec 3.
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Anti-hyperglycaemic potential of Psidium guajava raw fruit peel.番石榴生果皮的抗高血糖潜力
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Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice.肝脏特异性缺失脂解刺激脂蛋白受体引发小鼠全身性高脂血症。
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10
Protective effects of morroniside isolated from Corni Fructus against renal damage in streptozotocin-induced diabetic rats.山茱萸中分离出的莫诺苷对链脲佐菌素诱导的糖尿病大鼠肾损伤的保护作用。
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刺芹对链脲佐菌素诱导的糖尿病大鼠的降血脂活性

Hypolipidemic Activity of Eryngium carlinae on Streptozotocin-Induced Diabetic Rats.

作者信息

Noriega-Cisneros Ruth, Ortiz-Ávila Omar, Esquivel-Gutiérrez Edgar, Clemente-Guerrero Mónica, Manzo-Avalos Salvador, Salgado-Garciglia Rafael, Cortés-Rojo Christian, Boldogh Istvan, Saavedra-Molina Alfredo

机构信息

Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, 58030 Morelia, Michoacán, Mexico.

出版信息

Biochem Res Int. 2012;2012:603501. doi: 10.1155/2012/603501. Epub 2011 Nov 24.

DOI:10.1155/2012/603501
PMID:22162811
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3227232/
Abstract

Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes. The administration of E. carlinae extract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration of E. carlinae is able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus.

摘要

糖尿病（DM）是心血管并发症发生的重要危险因素。本研究旨在探讨长期给予刺芹乙醇提取物对链脲佐菌素（STZ）诱导的糖尿病大鼠血清中葡萄糖、肌酐、尿酸、总胆固醇和甘油三酯水平的影响。糖尿病大鼠血清中的甘油三酯、总胆固醇和尿酸水平升高。刺芹治疗可预防这些变化。刺芹提取物的给药降低了肌酐、尿酸、总胆固醇和甘油三酯的水平。因此，给予刺芹能够降低糖尿病中与心血管风险相关的高脂血症。