Department of Orthopaedics, Oslo University Hospital, University of Oslo, Kirkevn 166, 0407, Oslo, Norway.
Eur Spine J. 2012 Apr;21(4):681-90. doi: 10.1007/s00586-011-2145-3. Epub 2012 Jan 13.
A prospective study to evaluate whether certain baseline characteristics can predict outcome in patients treated with disc prosthesis or multidisciplinary rehabilitation.
Secondary analysis of 154 patients with chronic low back pain (LBP) for at least 1 year and degenerative discs originally recruited for a randomized trial. Outcome measures were Oswestry Disability Index (ODI) dichotomized to < or ≥15 points improvement and whether subjects were working at 2-year follow-up. A multiple logistic regression analysis was used.
In patients treated with disc prosthesis, long duration of LBP and high Fear-Avoidance Beliefs for work (FABQ-W) predicted worse ODI outcome [odds ratio (OR) = 1.9, 95% confidence interval (CI) 1.2-3.2 and OR = 1.7, CI 1.2-2.4 for every 5 years or 5 points]. Modic type I or II predicted better ODI outcome (OR = 5.3, CI 1.1-25.3). In patients treated with rehabilitation, a high ODI, low emotional distress (HSCL-25), and no daily narcotics predicted better outcome for ODI (OR = 2.5, CI 1.4-4.5 for every 5 ODI points, OR = 2.1, CI 1.1-5.1 for every 0.5 HSCL points and OR = 23.6, CI 2.1-266.8 for no daily narcotics). Low FABQ-W and working at baseline predicted working at 2-year follow-up after both treatments (OR = 1.3, CI 1.0-1.5 for every 5 points and OR = 4.1, CI 1.2-13.2, respectively).
Shorter duration of LBP, Modic type I or II changes and low FABQ-W were the best predictors of success after treatment with disc prosthesis, while high ODI, low distress and not using narcotics daily predicted better outcome of rehabilitation. Low FABQ-W and working predicted working at follow-up.
本前瞻性研究旨在评估某些基线特征是否可预测接受椎间盘假体或多学科康复治疗的患者的结局。
对 154 例慢性腰痛(LBP)至少 1 年且最初招募参加随机试验的退行性椎间盘患者进行二次分析。结局测量指标为 Oswestry 残疾指数(ODI),分为<或≥15 分改善和 2 年随访时是否工作。采用多元逻辑回归分析。
在接受椎间盘假体治疗的患者中,LBP 持续时间长和对工作的高恐惧-回避信念(FABQ-W)预测 ODI 结局较差[比值比(OR)=1.9,95%置信区间(CI)1.2-3.2 和 OR=1.7,CI 1.2-2.4,每 5 年或 5 分]。Modic 型 I 或 II 预测 ODI 结局更好(OR=5.3,CI 1.1-25.3)。在接受康复治疗的患者中,高 ODI、低情绪困扰(HSCL-25)和无每日麻醉剂预测 ODI 结局更好(OR=2.5,CI 1.4-4.5,每 5 个 ODI 点;OR=2.1,CI 1.1-5.1,每 0.5 个 HSCL 点;OR=23.6,CI 2.1-266.8,无每日麻醉剂)。低 FABQ-W 和基线时工作预测两种治疗后 2 年随访时工作[OR=1.3,CI 1.0-1.5,每 5 分;OR=4.1,CI 1.2-13.2]。
LBP 持续时间较短、Modic 型 I 或 II 改变和低 FABQ-W 是椎间盘假体治疗成功的最佳预测因素,而高 ODI、低痛苦和不每日使用麻醉剂预测康复结局更好。低 FABQ-W 和工作预测随访时工作。