Department of Microbiology, Biochemistry, Biotechnology and Biotechnology, University of Maribor, Faculty of Agriculture and Life Sciences, Pivola 10, 2311 Hoče, Slovenia.
Nutrients. 2010 Jun;2(6):611-25. doi: 10.3390/nu2060611. Epub 2010 Jun 1.
New eating habits, actual trends in production and consumption have a health, environmental and social impact. The European Union is fighting diseases characteristic of a modern age, such as obesity, osteoporosis, cancer, diabetes, allergies and dental problems. Developed countries are also faced with problems relating to aging populations, high energy foods, and unbalanced diets. The potential of nutraceuticals/functional foods/food supplements in mitigating health problems, especially in the gastrointestinal (GI) tract, is discussed. Certain members of gut microflora (e.g., probiotic/protective strains) play a role in the host health due to its involvement in nutritional, immunologic and physiological functions. The potential mechanisms by which nutraceuticals/functional foods/food supplements may alter a host's health are also highlighted in this paper. The establishment of novel functional cell models of the GI and analytical tools that allow tests in controlled experiments are highly desired for gut research.
新的饮食习惯、实际的生产和消费趋势对健康、环境和社会都有影响。欧盟正在与一些现代疾病作斗争,如肥胖、骨质疏松、癌症、糖尿病、过敏和牙科问题。发达国家还面临着与人口老龄化、高能量食品和饮食不均衡相关的问题。本文讨论了营养保健品/功能性食品/食品补充剂在缓解健康问题,特别是在胃肠道(GI)方面的潜力。由于肠道微生物群的某些成员(如益生菌/保护性菌株)参与了营养、免疫和生理功能,因此它们在宿主健康中发挥作用。本文还强调了营养保健品/功能性食品/食品补充剂可能改变宿主健康的潜在机制。建立新型的胃肠道功能细胞模型和允许在对照实验中进行测试的分析工具,对于胃肠道研究非常需要。