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本文引用的文献

1
Quantitative comparison of the cross-protection induced by tick-borne encephalitis virus vaccines based on European and Far Eastern virus subtypes.基于欧洲和远东病毒亚型的蜱传脑炎病毒疫苗的交叉保护作用的定量比较。
Vaccine. 2012 Feb 1;30(6):1165-9. doi: 10.1016/j.vaccine.2011.12.013. Epub 2011 Dec 14.
2
Tick-borne encephalitis in Europe, 2007 to 2009.2007年至2009年欧洲的蜱传脑炎
Euro Surveill. 2011 Sep 29;16(39):19976. doi: 10.2807/ese.16.39.19976-en.
3
Tick-borne encephalitis 2010: epidemiology, risk areas, and virus strains in Europe and Asia-an overview.2010 年虫媒脑炎：在欧洲和亚洲的流行病学、风险地区和病毒株概述。
Ticks Tick Borne Dis. 2011 Mar;2(1):2-15. doi: 10.1016/j.ttbdis.2010.10.007. Epub 2010 Dec 17.
4
Cytomegalovirus neutralization by hyperimmune and standard intravenous immunoglobulin preparations.巨细胞病毒中和作用的高免疫和标准静脉注射免疫球蛋白制剂。
Transplantation. 2011 Aug 15;92(3):267-70. doi: 10.1097/TP.0b013e318224115e.
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A tick-borne encephalitis virus vaccine based on the European prototype strain induces broadly reactive cross-neutralizing antibodies in humans.一种基于欧洲原型株的蜱传脑炎病毒疫苗可诱导人类产生广泛反应性的交叉中和抗体。
J Infect Dis. 2011 Jun 1;203(11):1556-64. doi: 10.1093/infdis/jir122.
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Increasing West Nile virus antibody titres in central European plasma donors from 2006 to 2010.2006 年至 2010 年期间，中欧血浆捐献者中寨卡病毒抗体滴度增加。
Euro Surveill. 2011 Mar 10;16(10):19812. doi: 10.2807/ese.16.10.19812-en.
7
Neutralization of different echovirus serotypes by individual lots of intravenous immunoglobulin.不同肠道病毒血清型被单批静脉注射用免疫球蛋白中和。
J Med Virol. 2011 Feb;83(2):305-10. doi: 10.1002/jmv.21980.
8
Human IgG subclasses: in vitro neutralization of and in vivo protection against West Nile virus.人免疫球蛋白亚类：体外中和及体内预防西尼罗河病毒的作用。
J Virol. 2011 Feb;85(4):1896-9. doi: 10.1128/JVI.02155-10. Epub 2010 Dec 1.
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Tick borne encephalitis TBE--vaccination in non-endemic countries.蜱传脑炎 TBE—非流行国家的疫苗接种。
Travel Med Infect Dis. 2010 Jul;8(4):251-6. doi: 10.1016/j.tmaid.2010.05.007. Epub 2010 Jun 25.
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Tick-borne encephalitis: pathogenesis and clinical implications.蜱传脑炎：发病机制与临床意义。
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不同免疫球蛋白制剂中的蜱传脑炎病毒中和抗体

Tick-borne encephalitis virus-neutralizing antibodies in different immunoglobulin preparations.

作者信息

Rabel Philip O, Planitzer Christina B, Farcet Maria R, Kreil Thomas R

机构信息

Global Pathogen Safety, Baxter BioScience, Vienna, Austria.

出版信息

Clin Vaccine Immunol. 2012 Apr;19(4):623-5. doi: 10.1128/CVI.05705-11. Epub 2012 Feb 29.

DOI:10.1128/CVI.05705-11
PMID:22379062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3318267/
Abstract

Patients with primary immunodeficiency (PIDs) depend on the presence of a variety of antibody specificities in intravenous immunoglobulin (IVIG). Using the tick-borne encephalitis virus (TBEV), geographic variability in IVIG antibody content was shown. Care should therefore be exercised when treating PIDs in a given geography, as only locally sourced plasma contains the antibody specificities against the circulating pathogens in the given locality.

摘要

原发性免疫缺陷（PID）患者依赖静脉注射免疫球蛋白（IVIG）中多种抗体特异性的存在。利用蜱传脑炎病毒（TBEV），已显示出IVIG抗体含量存在地理差异。因此，在特定地区治疗PID时应谨慎，因为只有当地来源的血浆才含有针对该地区循环病原体的抗体特异性。