Department of Human Genetics, Sri Ramachandra University, Porur, India.
Int J Nanomedicine. 2012;7:1043-60. doi: 10.2147/IJN.S25182. Epub 2012 Feb 23.
The focus on nanotechnology in cancer treatment and diagnosis has intensified due to the serious side effects caused by anticancer agents as a result of their cytotoxic actions on normal cells. This nonspecific action of chemotherapy has awakened a need for formulations capable of definitive targeting with enhanced tumor-killing. Nanooncology, the application of nanobiotechnology to the management of cancer, is currently the most important area of nanomedicine. Currently several nanomaterial-based drug-delivery systems are in vogue and several others are in various stages of development. Tumor-targeted drug-delivery systems are envisioned as magic bullets for cancer therapy and several groups are working globally for development of robust systems.
由于抗癌药物对正常细胞的细胞毒性作用而导致的严重副作用，癌症治疗和诊断中的纳米技术研究受到了重视。这种化疗的非特异性作用唤醒了人们对能够明确靶向并增强肿瘤杀伤的制剂的需求。纳米肿瘤学是将纳米生物技术应用于癌症管理的领域，是当前纳米医学最重要的领域。目前，有几种基于纳米材料的药物传递系统正在流行，还有几种处于不同的开发阶段。肿瘤靶向药物传递系统被视为癌症治疗的“神奇子弹”，全球有几个研究小组正在致力于开发强大的系统。
