Department of Pharmacology, University College of Medical Sciences (University of Delhi), Delhi, India.
Inflammopharmacology. 2012 Dec;20(6):343-6. doi: 10.1007/s10787-012-0134-8. Epub 2012 Apr 4.
The present study was performed to explore the effect of aqueous extract of Aloe vera on parameters of humoral and cell-mediated immunity.
Delayed-type hypersensitivity was assessed by measuring foot pad thickness following sensitisation by keyhole limpet haemocyanin injection and subsequently challenged by the same. Humoral immunity was assessed by measurement of haemagglutination titre to sheep red blood cells.
Aloe vera (400 mg/kg, p.o.) produced a significant decrease in foot pad thickness compared with the control group, and also significantly enhanced the secondary humoral immune response.
Thus, these findings suggest that A. vera can modulate immune response by augmenting secondary humoral immunity and decreasing cell-mediated immunity.
本研究旨在探讨库拉索芦荟水提物对体液免疫和细胞免疫参数的影响。
通过注射血蓝蛋白致敏后，再用相同物质进行攻毒，测量足垫厚度来评估迟发型超敏反应。通过测量对绵羊红细胞的血凝滴度来评估体液免疫。
与对照组相比，芦荟（400mg/kg，po）显著降低了足垫厚度，并且显著增强了二次体液免疫反应。
因此，这些发现表明，库拉索芦荟可以通过增强二次体液免疫和降低细胞免疫来调节免疫反应。
