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"西班牙加泰罗尼亚地区初级卫生保健中的骨质疏松性骨折负担:一项基于人群的研究"。

"Burden of osteoporotic fractures in primary health care in Catalonia (Spain): a population-based study".

机构信息

Institut Català de la Salut, Barcelona, Spain.

出版信息

BMC Musculoskelet Disord. 2012 May 28;13:79. doi: 10.1186/1471-2474-13-79.

Abstract

BACKGROUND

Knowledge on the epidemiology of non-hip fractures in Spain is limited and somewhat outdated. Using computerized primary care records from the SIDIAP database, we derived age and sex-specific fracture incidence rates for the region of Catalonia during the year 2009.

METHODS

The SIDIAP database contains quality-checked clinical information from computerized medical records of a representative sample of >5,800,000 patients (80% of the population of Catalonia). We conducted a retrospective cohort study including all patients aged ≥50 years, and followed them from January 1 to December 31, 2009. Major osteoporotic fractures registered in SIDIAP were ascertained using ICD-10 codes and validated by comparing data to hospital admission and patient-reported fractures records. Incidence rates and 95% confidence intervals were calculated.

RESULTS

In total, 2,011,430 subjects were studied (54.6% women). Overall fracture rates were 10.91/1,000 person-years (py) [95%CI 10.89-10.92]: 15.18/1,000 py [15.15-15.21] in women and 5.78/1,000 py [5.76-5.79] in men. The most common fracture among women was wrist/forearm (3.86/1,000 py [3.74-3.98]), while among men it was clinical spine (1.25/1,000 py [1.18-1.33]). All fracture rates increased with age, but varying patterns were observed: while most of the fractures (hip, proximal humerus, clinical spine and pelvis) increased continuously with age, wrist and multiple rib fractures peaked at age 75-80 and then reached a plateau.

CONCLUSIONS

Our study provides local estimates of age, sex and site-specific fracture burden in primary health care, which will be helpful for health-care planning and delivery. A proportion of fractures are not reported in primary care records, leading to underestimation of fracture incidence rates in these data.

摘要

背景

西班牙非髋部骨折的流行病学知识有限且有些陈旧。我们利用 SIDIAP 数据库的计算机化初级保健记录,得出了 2009 年加泰罗尼亚地区按年龄和性别划分的骨折发病率。

方法

SIDIAP 数据库包含了来自超过 580 万患者(加泰罗尼亚地区 80%的人口)计算机化医疗记录的经过质量检查的临床信息。我们进行了一项回顾性队列研究,纳入了所有年龄≥50 岁的患者,并从 2009 年 1 月 1 日至 12 月 31 日对其进行随访。SIDIAP 中登记的主要骨质疏松性骨折使用 ICD-10 代码确定,并通过与医院入院和患者报告的骨折记录进行比较来验证。计算发病率和 95%置信区间。

结果

共有 2011430 名患者纳入研究(54.6%为女性)。总体骨折发生率为 10.91/1000 人年(95%CI 10.89-10.92):女性为 15.18/1000 人年(15.15-15.21),男性为 5.78/1000 人年(5.76-5.79)。女性中最常见的骨折是腕/前臂(3.86/1000 人年[3.74-3.98]),而男性中最常见的骨折是临床脊柱(1.25/1000 人年[1.18-1.33])。所有骨折发生率均随年龄增长而增加,但存在不同模式:大多数骨折(髋部、近端肱骨、临床脊柱和骨盆)随年龄持续增加,而腕部和多处肋骨骨折在 75-80 岁时达到峰值,然后达到平台期。

结论

我们的研究提供了初级保健中按年龄、性别和部位划分的骨折负担的当地估计值,这将有助于医疗保健规划和服务的提供。初级保健记录中并未报告一部分骨折,这导致这些数据中骨折发病率的低估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05c4/3489545/8e911e9f68de/1471-2474-13-79-1.jpg

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