Center of Excellence in Biotechnology Research, King Saud University, Riyadh, KSA.
Endocr J. 2012;59(12):1057-63. doi: 10.1507/endocrj.ej12-0167. Epub 2012 Jul 13.
We report the dietary intake of selected nutrients in apparently healthy adults and children and its correlation with circulating levels of serum leptin and resistin. In this observational study, 47 Saudi children (mean age 13.1 ± 2.8 year) and 47 adults (mean age 45.7 ± 10.5 year) were recruited. Anthropometric data and lipid profile were obtained. Food intake was assessed by a food questionnaire and a 24-hour diet recall method. The dietary intake of selected nutrients was compared with the estimated average requirement (EAR) or adequate intake (AI) for establishing nutritional status. Results demonstrated that the levels of choline and calcium intake were significantly lower than the EAR in adults (p= 0.01 and 0.04, respectively) and relatively low in children. The level of manganese in adults was significantly higher (p= 0.02) than their AI level. The increasing levels of dietary vitamin B6 and B12 were associated with a significant increase in serum concentrations of leptin in adults and children (p=0.02). Overall, the dietary intakes of selected nutrients in Saudi adults and children were not adequate with most of them below cut-off EAR values except for essential amino acids.
我们报告了在看似健康的成年人和儿童中,选定营养素的饮食摄入量及其与循环血清瘦素和抵抗素水平的相关性。在这项观察性研究中,招募了 47 名沙特儿童(平均年龄 13.1 ± 2.8 岁)和 47 名成年人(平均年龄 45.7 ± 10.5 岁)。获得了人体测量数据和血脂谱。通过食物问卷和 24 小时饮食回忆法评估食物摄入量。将选定营养素的饮食摄入量与估计平均需求量 (EAR) 或适宜摄入量 (AI) 进行比较,以确定营养状况。结果表明,成年人的胆碱和钙摄入量水平明显低于 EAR(分别为 p=0.01 和 0.04),儿童的摄入量相对较低。成年人的锰水平明显高于其 AI 水平(p=0.02)。饮食中维生素 B6 和 B12 水平的升高与成年人和儿童血清瘦素浓度的显著升高相关(p=0.02)。总体而言,沙特成年人和儿童的选定营养素饮食摄入量不足,除必需氨基酸外,大多数营养素的摄入量均低于临界 EAR 值。