Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford OX1 3PT, UK.
Neuron. 2012 Sep 20;75(6):948-50. doi: 10.1016/j.neuron.2012.09.001.
The 3Rs--replacement, reduction, and refinement--are aimed at minimizing the welfare costs to animals used in research. Some neuroscientists fear that implementing the 3Rs will prohibit essential studies. Others view them as fundamental ethical principles that improve the quality of research. A regulatory system that integrates science and welfare is most likely to deliver public confidence.
3Rs（替代、减少和优化）旨在将用于研究的动物的福利成本降到最低。一些神经科学家担心实施 3Rs 会禁止必要的研究。另一些人则认为它们是提高研究质量的基本伦理原则。将科学和福利相结合的监管体系最有可能赢得公众的信任。
