惊人的相似性：GATA-3 调控 ILC2 和 Th2 细胞。
Striking similarity: GATA-3 regulates ILC2 and Th2 cells.
机构信息
Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
出版信息
Immunity. 2012 Oct 19;37(4):589-91. doi: 10.1016/j.immuni.2012.10.002.
Abstract
Innate lymphoid cells (ILCs) and T helper (Th) cells share similar effector functions. In this issue of Immunity, Hoyler et al. (2012) and Mjosberg et al. (2012) demonstrate that GATA-3, a Th2 regulator, controls ILC2 differentiation, maintenance, and function.
摘要
先天淋巴细胞 (ILCs) 和辅助性 T 细胞 (Th) 具有相似的效应功能。在本期《免疫》杂志中，Hoyler 等人和 Mjosberg 等人分别证明，Th2 调节因子 GATA-3 控制着 ILC2 的分化、维持和功能。
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本文引用的文献
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The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.转录因子 GATA-3 控制着 2 型先天淋巴细胞的细胞命运和维持。
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