Department of Kinesiology, University of Connecticut, 2095 Hillside Road, U-1110, Storrs, CT 06269-1110, USA.
J Athl Train. 2012 Nov-Dec;47(6):655-63. doi: 10.4085/1062-6050-47.5.09.
Cold-water immersion is the criterion standard for treatment of exertional heat illness. Cryotherapy and water immersion also have been explored as ergogenic or recovery aids. The kinetics of inflammatory markers, such as interleukin-6 (IL-6), during cold-water immersion have not been characterized.
To characterize serum IL-6 responses to water immersion at 2 temperatures and, therefore, to initiate further research into the multidimensional benefits of immersion and the evidence-based selection of specific, optimal immersion conditions by athletic trainers.
Controlled laboratory study.
Human performance laboratory Patients or Other Participants: Eight college-aged men (age = 22 ± 3 years, height = 1.76 ± 0.08 m, mass = 77.14 ± 9.77 kg, body fat = 10% ± 3%, and maximal oxygen consumption = 50.48 ± 4.75 mL·kg(-1) min(-1)).
Participants were assigned randomly to receive either cold (11.70°C ± 2.02°C, n = 4) or warm (23.50°C ± 1.00°C, n = 4) water-bath conditions after exercise in the heat (temperature = 37°C, relative humidity = 52%) for 90 minutes or until volitional cessation.
Whole-body cooling rates were greater in the cold water-bath condition for the first 6 minutes of water immersion, but during the 90-minute, postexercise recovery, participants in the warm and cold water-bath conditions experienced similar overall whole-body cooling. Heart rate responses were similar for both groups. Participants in the cold water-bath condition experienced an overall slight increase (30.54% ± 77.37%) in IL-6 concentration, and participants in the warm water-bath condition experienced an overall decrease (-69.76% ± 15.23%).
We have provided seed evidence that cold-water immersion is related to subtle IL-6 increases from postexercise values and that warmer water-bath temperatures might dampen this increase. Further research will elucidate any anti-inflammatory benefit associated with water-immersion treatment and possible multidimensional uses of cooling therapies.
冷水浸泡是治疗运动性热病的标准方法。冷疗和水浸也被探索作为运动增益或恢复辅助手段。在冷水浸泡过程中，炎症标志物如白细胞介素-6（IL-6）的动力学尚未得到描述。
描述两种温度下水浸对血清 IL-6 反应的特征，从而进一步研究浸浴的多维益处，并为运动训练员选择特定的、最佳的浸浴条件提供循证依据。
对照实验室研究。
人体性能实验室
八名大学生年龄（22 ± 3 岁），身高（1.76 ± 0.08 米），体重（77.14 ± 9.77 千克），体脂（10% ± 3%）和最大摄氧量（50.48 ± 4.75 毫升/千克/分钟）。
参与者随机分配接受冷水（11.70°C ± 2.02°C，n = 4）或温水（23.50°C ± 1.00°C，n = 4）水浴条件，在热环境（温度为 37°C，相对湿度为 52%）中运动 90 分钟或直至自愿停止。
在水浸的前 6 分钟，全身冷却速率在冷水浴条件下较大，但在 90 分钟的运动后恢复期，温水和冷水浴条件下的参与者经历了相似的全身整体冷却。两组的心率反应相似。冷水浴组的 IL-6 浓度总体略有升高（30.54% ± 77.37%），温水浴组的 IL-6 浓度总体降低（-69.76% ± 15.23%）。
我们提供了初步证据表明，冷水浸泡与运动后 IL-6 升高有关，而较暖的水浴温度可能会抑制这种升高。进一步的研究将阐明与水浸治疗相关的任何抗炎益处以及冷却疗法的可能多维用途。
