急性运动热应激后浸水疗法对白细胞介素-6 反应的影响：一项初步研究。

Interleukin-6 responses to water immersion therapy after acute exercise heat stress: a pilot investigation.

机构信息

Department of Kinesiology, University of Connecticut, 2095 Hillside Road, U-1110, Storrs, CT 06269-1110, USA.

出版信息

J Athl Train. 2012 Nov-Dec;47(6):655-63. doi: 10.4085/1062-6050-47.5.09.

DOI:10.4085/1062-6050-47.5.09

PMID:23182014

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3499890/

Abstract

CONTEXT

Cold-water immersion is the criterion standard for treatment of exertional heat illness. Cryotherapy and water immersion also have been explored as ergogenic or recovery aids. The kinetics of inflammatory markers, such as interleukin-6 (IL-6), during cold-water immersion have not been characterized.

OBJECTIVE

To characterize serum IL-6 responses to water immersion at 2 temperatures and, therefore, to initiate further research into the multidimensional benefits of immersion and the evidence-based selection of specific, optimal immersion conditions by athletic trainers.

DESIGN

Controlled laboratory study.

SETTING

Human performance laboratory Patients or Other Participants: Eight college-aged men (age = 22 ± 3 years, height = 1.76 ± 0.08 m, mass = 77.14 ± 9.77 kg, body fat = 10% ± 3%, and maximal oxygen consumption = 50.48 ± 4.75 mL·kg(-1) min(-1)).

MAIN OUTCOME MEASURES

Participants were assigned randomly to receive either cold (11.70°C ± 2.02°C, n = 4) or warm (23.50°C ± 1.00°C, n = 4) water-bath conditions after exercise in the heat (temperature = 37°C, relative humidity = 52%) for 90 minutes or until volitional cessation.

RESULTS

Whole-body cooling rates were greater in the cold water-bath condition for the first 6 minutes of water immersion, but during the 90-minute, postexercise recovery, participants in the warm and cold water-bath conditions experienced similar overall whole-body cooling. Heart rate responses were similar for both groups. Participants in the cold water-bath condition experienced an overall slight increase (30.54% ± 77.37%) in IL-6 concentration, and participants in the warm water-bath condition experienced an overall decrease (-69.76% ± 15.23%).

CONCLUSIONS

We have provided seed evidence that cold-water immersion is related to subtle IL-6 increases from postexercise values and that warmer water-bath temperatures might dampen this increase. Further research will elucidate any anti-inflammatory benefit associated with water-immersion treatment and possible multidimensional uses of cooling therapies.

摘要

背景

冷水浸泡是治疗运动性热病的标准方法。冷疗和水浸也被探索作为运动增益或恢复辅助手段。在冷水浸泡过程中，炎症标志物如白细胞介素-6（IL-6）的动力学尚未得到描述。

目的

描述两种温度下水浸对血清 IL-6 反应的特征，从而进一步研究浸浴的多维益处，并为运动训练员选择特定的、最佳的浸浴条件提供循证依据。

设计

对照实验室研究。

地点

人体性能实验室

患者或其他参与者

八名大学生年龄（22 ± 3 岁），身高（1.76 ± 0.08 米），体重（77.14 ± 9.77 千克），体脂（10% ± 3%）和最大摄氧量（50.48 ± 4.75 毫升/千克/分钟）。

主要观察指标

参与者随机分配接受冷水（11.70°C ± 2.02°C，n = 4）或温水（23.50°C ± 1.00°C，n = 4）水浴条件，在热环境（温度为 37°C，相对湿度为 52%）中运动 90 分钟或直至自愿停止。

结果

在水浸的前 6 分钟，全身冷却速率在冷水浴条件下较大，但在 90 分钟的运动后恢复期，温水和冷水浴条件下的参与者经历了相似的全身整体冷却。两组的心率反应相似。冷水浴组的 IL-6 浓度总体略有升高（30.54% ± 77.37%），温水浴组的 IL-6 浓度总体降低（-69.76% ± 15.23%）。