Pediatric Laboratory, Retina Foundation of the Southwest, Dallas, TX 75231, USA.
Prog Retin Eye Res. 2013 Mar;33:67-84. doi: 10.1016/j.preteyeres.2012.11.001. Epub 2012 Nov 29.
Amblyopia is the most common cause of monocular visual loss in children, affecting 1.3%-3.6% of children. Current treatments are effective in reducing the visual acuity deficit but many amblyopic individuals are left with residual visual acuity deficits, ocular motor abnormalities, deficient fine motor skills, and risk for recurrent amblyopia. Using a combination of psychophysical, electrophysiological, imaging, risk factor analysis, and fine motor skill assessment, the primary role of binocular dysfunction in the genesis of amblyopia and the constellation of visual and motor deficits that accompany the visual acuity deficit has been identified. These findings motivated us to evaluate a new, binocular approach to amblyopia treatment with the goals of reducing or eliminating residual and recurrent amblyopia and of improving the deficient ocular motor function and fine motor skills that accompany amblyopia.
弱视是儿童单眼视力丧失的最常见原因，影响 1.3%-3.6%的儿童。目前的治疗方法可有效降低视力缺陷，但许多弱视患者仍存在残余视力缺陷、眼球运动异常、精细运动技能不足以及弱视复发的风险。通过使用心理物理学、电生理学、影像学、风险因素分析和精细运动技能评估相结合的方法，确定了双眼功能障碍在弱视发生中的主要作用，以及伴随视力缺陷的视觉和运动缺陷的组合。这些发现促使我们评估一种新的、双眼治疗弱视的方法，其目标是减少或消除残余和复发性弱视，并改善伴随弱视的眼球运动功能和精细运动技能缺陷。
